Evidence map›Paper›PMID 30446505›Full record

ArticleScience immunology2018

Single-cell transcriptional analysis reveals ILC-like cells in zebrafish.

Pedro P Hernández, Paulina M Strzelecka, Emmanouil I Athanasiadis, Dominic Hall, Ana F Robalo, Catherine M Collins, Pierre Boudinot, Jean-Pierre Levraud, Ana Cvejic

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 130 citations in OpenAlex.

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  12. Innate Lymphoid Cells Are the Rheostat of Immune Response in the Kidney.Journal of cellular and molecular medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Pedro P HernándezMacrophages et Développement de l'Immunité, Institut Pasteur, Paris, France. as889@cam.ac.uk jean-pierre.levraud@pasteur.fr pedro.hernandez-cerda@pasteur.fr.ORCID 0000-0002-2873-4298
Paulina M StrzeleckaDepartment of Haematology, University of Cambridge, Cambridge, UK.ORCID 0000-0003-0226-6788
Emmanouil I AthanasiadisDepartment of Haematology, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2771-5562
Dominic HallWellcome Trust-Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.ORCID 0000-0001-5284-609X
Ana F RobaloMacrophages et Développement de l'Immunité, Institut Pasteur, Paris, France.
Catherine M CollinsMarine Scotland Science, Marine Laboratory, Aberdeen, UK.
Pierre BoudinotInstitut National de la Recherche Agronomique, Virologie et Immunologie Moléculaire, Jouy-en-Josas, France.ORCID 0000-0002-7490-9677
Jean-Pierre LevraudMacrophages et Développement de l'Immunité, Institut Pasteur, Paris, France. as889@cam.ac.uk jean-pierre.levraud@pasteur.fr pedro.hernandez-cerda@pasteur.fr.ORCID 0000-0001-6775-2416
Ana CvejicDepartment of Haematology, University of Cambridge, Cambridge, UK. as889@cam.ac.uk jean-pierre.levraud@pasteur.fr pedro.hernandez-cerda@pasteur.fr.ORCID 0000-0003-3204-9311
Wellcome/MRC Cambridge Stem Cell Institute · GBCentre National de la Recherche Scientifique · FRMarine Scotland · GBVirologie et Immunologie Moléculaires · FR

Funding

Cancer Research UK 14953Cancer Research UK C45041/A14953European Research Council 677501Medical Research Council MC_PC_12009Wellcome Trust
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are important mediators of the immune response and homeostasis in barrier tissues of mammals. However, the existence and function of ILCs in other vertebrates are poorly understood. Here, we use single-cell RNA sequencing to generate a comprehensive atlas of zebrafish lymphocytes during tissue homeostasis and after immune challenge. We profiled 14,080 individual cells from the gut of wild-type zebrafish, as well as of

Indexed as

Single-Cell AnalysisTranscription, GeneticAnimalsImmunity, InnateLymphocytesZebrafish

Identifiers

PMID30446505
PMCPMC6258902
OpenAlexW2901405427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.