Evidence map›Paper›PMID 30445985›Full record

ReviewReproductive biology and endocrinology : RB&E2018

Radiations and male fertility.

Kavindra Kumar Kesari, Ashok Agarwal, Ralf Henkel

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04541459 (Validation of New Devices Against Ambient Electromagnetic Radiation), which is not on this map. Cited by 100 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 1 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04541459 early_phase1unknown statusnot on this mapstarted 2020, after this paper: background citation

Validation of New Devices Against Ambient Electromagnetic Radiation: A Randomized Double Blind Controlled Study

TypeinterventionalSponsorWaveguard GmbHRan2020 to 2021Enrolled40ConditionsMale InfertilityArmsnew device against ambient electromagnetic radiation, sham device against ambient electromagnetic radiation
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 1 synthesis or guideline pooled it, 270 citations in OpenAlex.

  1. Pooled it
  2. A systematic review of mobile phone use and pregnancy and fetal outcomes.Journal of exposure science & environmental epidemiology · 2026
    Review
  3. Review
  4. Article
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  7. Article
  8. Article
  9. Review
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  11. Review
  12. Advances in Research on Models of Oligoasthenozoospermia.Reproductive sciences (Thousand Oaks, Calif.) · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
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  19. Review
  20. Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Kavindra Kumar KesariDepartment of Applied Physics, Aalto University, Espoo, Finland.
Ashok AgarwalAmerican Center for Reproductive Medicine, Cleveland Clinic, Mail Code X-11, 10681 Carnegie Avenue, Cleveland, OH, 44195, USA. agarwaa@ccf.org.ORCID http://orcid.org/0000-0003-0585-1026
Ralf HenkelDepartment of Medical Bioscience, University of the Western Cape, Robert Sobukwe Road, Bellville, 7535, South Africa.
Aalto University · FICleveland Clinic · USUniversity of the Western Cape · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat and extreme exposure to pesticides, radiations, radioactivity and other hazardous substances. We are surrounded by several types of ionizing and non-ionizing radiations and both have recognized causative effects on spermatogenesis. Since it is impossible to cover all types of radiation sources and their biological effects under a single title, this review is focusing on radiation deriving from cell phones, laptops, Wi-Fi and microwave ovens, as these are the most common sources of non-ionizing radiations, which may contribute to the cause of infertility by exploring the effect of exposure to radiofrequency radiations on the male fertility pattern. From currently available studies it is clear that radiofrequency electromagnetic fields (RF-EMF) have deleterious effects on sperm parameters (like sperm count, morphology, motility), affects the role of kinases in cellular metabolism and the endocrine system, and produces genotoxicity, genomic instability and oxidative stress. This is followed with protective measures for these radiations and future recommendations. The study concludes that the RF-EMF may induce oxidative stress with an increased level of reactive oxygen species, which may lead to infertility. This has been concluded based on available evidences from in vitro and in vivo studies suggesting that RF-EMF exposure negatively affects sperm quality.

Indexed as

Cell PhoneElectromagnetic FieldsEnvironmental ExposureFertilityHumansInfertility, MaleMaleOxidative StressRadio WavesSpermatozoa

Identifiers

PMID30445985
PMCPMC6240172
OpenAlexW2900507437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.