Evidence map›Paper›PMID 30445913›Full record

ArticleBMC infectious diseases2018

Case report: two confirmed cases of human Seoul virus infections in Indonesia.

Khie Chen Lie, Mochamad Helmi Aziz, Herman Kosasih, Aaron Neal, Caleb Leonardo Halim, Wahyu Nawang Wulan, Muhammad Karyana, Usman Hadi

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Khie Chen LieUniversitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
Mochamad Helmi AzizINA-RESPOND, NIHRD, Ministry of Health Republic of Indonesia Building 4 (Laboratorium Terpadu), 5th Floor, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia.
Herman KosasihINA-RESPOND, NIHRD, Ministry of Health Republic of Indonesia Building 4 (Laboratorium Terpadu), 5th Floor, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia. hkosasih@ina-respond.net.ORCID http://orcid.org/0000-0001-7844-3643
Aaron NealNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.
Caleb Leonardo HalimINA-RESPOND, NIHRD, Ministry of Health Republic of Indonesia Building 4 (Laboratorium Terpadu), 5th Floor, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia.
Wahyu Nawang WulanINA-RESPOND, NIHRD, Ministry of Health Republic of Indonesia Building 4 (Laboratorium Terpadu), 5th Floor, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia.
Muhammad KaryanaNational Institute of Health Research and Development (NIHRD), Ministry of Health Republic of Indonesia, Jakarta, Indonesia.
Usman HadiUniversitas Airlangga, Dr. Soetomo Hospital, Surabaya, Indonesia.
Ministry of Health · IDAirlangga University · IDNational Institutes of Health · USUniversity of Indonesia · ID

Funding

CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003I
6 · The paper itself

Abstract

backgroundSeoul virus (SEOV) is a member of hantavirus family, which is transmitted to humans by Rattus rattus and Rattus norvegicus. Diagnosing SEOV infection is difficult because the clinical presentations are often undifferentiated with other viral or bacterial infections and assays to test antibodies seroconversion and RNA detection are not available in resource-limited setting like Indonesia. CASE PRESENTATION: We report two confirmed cases of SEOV infection from Indonesia. Here, we illustrate the clinical presentations, hematology and biochemistry profiles, and outcomes of the two cases. Phylogenetic analysis revealed that SEOV sequences have highest homology to isolates obtained from rodents in Indonesia.

conclusionsThis report highlights the importance of considering SEOV infection in febrile patients with lymphopenia, thrombocytopenia, and elevation of liver enzyme despite the absence of hemorrhagic manifestations and renal syndromes. The public health importance of rodent-borne diseases such as SEOV infection urges an integrated epidemiological surveillance both in humans and rodents in Indonesia.

Indexed as

AdultAnimalsDiagnosis, DifferentialFemaleFeverHemorrhagic Fever with Renal SyndromeHumansIndonesiaMaleMiddle AgedPhylogenyRatsRNA, ViralRodentiaSeoul virusRNA, ViralDetectionIndonesiaSeoul virus

Identifiers

PMID30445913
PMCPMC6240170
OpenAlexW2901120682

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.