Evidence map›Paper›PMID 30445728›Full record

ArticleInternational journal of molecular sciences2018

Molecular Docking, Computational, and Antithrombotic Studies of Novel 1,3,4-Oxadiazole Derivatives.

Majda Batool, Affifa Tajammal, Firdous Farhat, Francis Verpoort, Zafar A K Khattak, Mehr-un-Nisa, Muhammad Shahid, Hafiz Adnan Ahmad, Munawar Ali Munawar, Muhammad Zia-Ur-Rehman and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Royal Society open science · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Majda BatoolInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. majdabatool12@gmail.com.
Affifa TajammalInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. affifa.tajammal@yahoo.com.
Firdous FarhatInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. farhatfirdous555@gmail.com.
Francis VerpoortLaboratory of Organometallics, Catalysis and Ordered Materials, State Key Laboratory of Advanced Technology for Material Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China. Francis.Verpoort@ghent.ac.kr.ORCID 0000-0002-5184-5500
Zafar A K KhattakLaboratory of Organometallics, Catalysis and Ordered Materials, State Key Laboratory of Advanced Technology for Material Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China. zafarchem_qau@yahoo.com.
Mehr-un-NisaInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. anmehrunnisa@gmail.com.
Muhammad ShahidInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. mshahidkhan403@gmail.com.
Hafiz Adnan AhmadInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. adnan.ahmad.pu@hotmail.com.ORCID 0000-0002-6775-7169
Munawar Ali MunawarInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. munawaralimunawar@yahoo.com.
Muhammad Zia-Ur-RehmanApplied Chemistry Research Centre, PCSIR Laboratories Complex, Ferozpur Road, Lahore 54600, Pakistan. rehman_pcsir@hotmail.com.
Muhammad Asim Raza BasraInstitute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan. asimbasra@gmail.com.ORCID 0000-0002-4242-0025
University of the Punjab · PKWuhan University of Technology · CNMinistry of Education of the People's Republic of China · CNPakistan Council of Scientific & Industrial Research · PK

Funding

Higher Education Commision, Pakistan PIN:117-6030-PS7-077
6 · The paper itself

Abstract

A new series of 1,3,4-oxadiazoles derivatives was synthesized, characterized, and evaluated for their in vitro and in vivo anti-thrombotic activity. Compounds (

Indexed as

Molecular Docking SimulationAdultAnimalsAnticoagulantsBinding SitesFibrinolytic AgentsHumansImaging, Three-DimensionalMaleOxadiazolesRats, Sprague-DawleyStatic ElectricityTime FactorsYoung Adult1,3,4-oxadiazoleAnticoagulantsFibrinolytic AgentsOxadiazolescardiovascular diseases (CD)coronary heart disease (CHD)factor Xa (F-Xa)N,N-dimethyl formamide (DMF)streptokinase (SK)tissue plasminogen activator (t-PA)urokinase (UK)

Identifiers

PMID30445728
PMCPMC6274789
OpenAlexW2889626712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.