Evidence map›Paper›PMID 30445717›Full record

ArticleViruses2018

Base-By-Base Version 3: New Comparative Tools for Large Virus Genomes.

Shin-Lin Tu, Jeannette P Staheli, Colum McClay, Kathleen McLeod, Timothy M Rose, Chris Upton

Abstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genome Analyses of Ten New Ape Adenoviruses with Similarity to HumanInternational journal of molecular sciences · 2022
    Article
  8. Poxvirus Recombination.Pathogens (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. A Comprehensive Analysis ofFrontiers in genetics · 2020
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shin-Lin TuBiochemistry and Microbiology, University of Victoria, Victoria, BC V8W 2Y2, Canada. cindytu@uvic.ca.ORCID 0000-0002-2677-7614
Jeannette P StaheliCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98101, USA. jeannette.staheli@seattlechildrens.org.
Colum McClayBiochemistry and Microbiology, University of Victoria, Victoria, BC V8W 2Y2, Canada. colummcclay@hotmail.com.
Kathleen McLeodBiochemistry and Microbiology, University of Victoria, Victoria, BC V8W 2Y2, Canada. kathleen_mcleod14@hotmail.com.
Timothy M RoseCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98101, USA. trose@u.washington.edu.
Chris UptonBiochemistry and Microbiology, University of Victoria, Victoria, BC V8W 2Y2, Canada. cupton@uvic.ca.ORCID 0000-0002-9019-8967

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2015-04953
6 · The paper itself

Abstract

Base-By-Base is a comprehensive tool for the creation and editing of multiple sequence alignments that is coded in Java and runs on multiple platforms. It can be used with gene and protein sequences as well as with large viral genomes, which themselves can contain gene annotations. This report describes new features added to Base-By-Base over the last 7 years. The two most significant additions are: (1) The recoding and inclusion of "consensus-degenerate hybrid oligonucleotide primers" (CODEHOP), a popular tool for the design of degenerate primers from a multiple sequence alignment of proteins; and (2) the ability to perform fuzzy searches within the columns of sequence data in multiple sequence alignments to determine the distribution of sequence variants among the sequences. The intuitive interface focuses on the presentation of results in easily understood visualizations and providing the ability to annotate the sequences in a multiple alignment with analytic and user data.

Indexed as

Computational BiologyGenomicsSoftwareVirusesASFVBase-By-BaseBBBbioinformaticscomparative genomicsMSApoxvirussoftwarevirus

Identifiers

PMID30445717
PMCPMC6265842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.