Evidence map›Paper›PMID 30445561›Full record

ArticleAmerican journal of hypertension2019

Heart-to-Brachium Pulse Wave Velocity as a Measure of Proximal Aortic Stiffness: MRI and Longitudinal Studies.

Jun Sugawara, Tsubasa Tomoto, Hirofumi Tanaka

Abstract readComparative Study
In one paragraph

Article in American journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Cross-sectional and longitudinal evaluation of heart-to-brachium pulse wave velocity for cardiovascular disease risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jun SugawaraHuman Informatics Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
Tsubasa TomotoHuman Informatics Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
Hirofumi TanakaDepartment of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStiffening of the proximal aorta is associated with heightened cardiovascular disease risks but can be quantified by limited methodologies (e.g., magnetic resonance imaging [MRI]). As an initial step to evaluate the emerging technique to assess proximal aortic stiffness via pulse wave velocity from the heart to the brachium (hbPWV), we determined the influences of aging on pulse wave velocity (PWV) and aortic hemodynamics.

methodUsing the cross-sectional and follow-up study designs, hbPWV was compared and evaluated in relation to other PWV in various arterial segments. Arterial path lengths were measured by the 3-dimensional arterial tracing of MRI.

resultsIn the cross-sectional study including 190 subjects (aged 19-79 years), hbPWV exhibited one of the largest age-related increases and a stronger correlation with age (r = 0.790) compared with the other measures of PWV including carotid-femoral PWV, brachial-ankle PWV, and PWV of muscular arteries (r = 0.445-0.688). In addition, hbPWV was correlated with aortic systolic blood pressure (BP) and augmentation index (r = 0.380 and 0.433, respectively) after controlling for brachial systolic BP. These results were confirmed by the 10-year follow-up study involving 84 individuals (53 years at baseline). The decadal changes in hbPWV were significantly correlated with the corresponding changes in several aortic hemodynamic variables (e.g., aortic systolic BP, augmentation pressure, and augmentation index) (r = 0.240-0.349).

conclusionsThe present findings indicate that hbPWV is a potential marker of proximal aortic stiffening that reflects age-related changes and aortic hemodynamics.

Indexed as

HemodynamicsMagnetic Resonance AngiographyPulse Wave AnalysisVascular StiffnessAdultAgedAge FactorsAgingAortaCardiovascular DiseasesCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID30445561
PMCPMC6331710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.