Observational studyThe Journal of antimicrobial chemotherapy2019
Appropriateness of antibiotic prescribing in the Emergency Department.
Observational study in The Journal of antimicrobial chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- Use of stewardship smartphone applications by physicians and prescribing of antimicrobials in hospitals: A systematic review.PloS one · 2020Pooled it
- Appropriateness of antibiotic selection at emergency department discharge and risk of 30-day adverse events in patients with acute exacerbation of COPD.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026Observational
- Emergency Department Clinicians' Needs for User-Centered Antibiotic Guideline: Insights from a Focus Group Interview.Infection & chemotherapy · 2026Article
- Deep learning analysis of 12-lead electrocardiograms for bloodstream infection prediction: a multi-center validation study.BMC medical informatics and decision making · 2026Article
- Antibiotic Use in the Emergency Department: A Retrospective Study in Indonesia.Antibiotics (Basel, Switzerland) · 2026Article
- Article
- The Invisible Excess: Too Long Antibiotic Duration in the Pediatric Emergency Care.Antibiotics (Basel, Switzerland) · 2026Article
- [Risk factors associated with inadequacy of empirical treatment in patients with sepsis and bacteremia attended in an emergency department].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026Observational
- Timing of Antibiotics in ICU Pneumonia: An Observational Association Between Early Treatment and Higher Mortality.Antibiotics (Basel, Switzerland) · 2026Article
- An open-source, configurable machine learning pipeline for predicting blood culture outcomes from routine haematology parameters.Access microbiology · 2026Article
- Clinical Gestalt to Predict Bacterial Infection and Mortality in Emergency Department Patients: A Prospective Observational Study.Journal of general internal medicine · 2026Observational
- Physician Feedback Reduces Antibiotic Prescribing for Uncomplicated Upper Respiratory Tract Infection in the Emergency Department.Antibiotics (Basel, Switzerland) · 2025Article
- Impact of antibiotic post-prescription authorization in resource-limited emergency rooms and acute care units during the COVID-19 pandemic.BMC emergency medicine · 2025Observational
- Health and Psychological Predictors of Antibiotic Use in Infancy and Fathers' Role.European journal of investigation in health, psychology and education · 2025Article
- Antimicrobial prescribing quality in Australian emergency departments: an analysis of the Hospital NAPS data set.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Antibiotic prescribing for skin infections: broader coverage in emergency settings and differences by race.Archives of dermatological research · 2024Article
- Antibiotic prescription patterns in the emergency department of a tertiary healthcare center in Nepal: a descriptive cross-sectional study.The Journal of international medical research · 2024Article
- Follow-up of patients with urinary tract infections discharged from the emergency department: a mixed methods study.The Journal of antimicrobial chemotherapy · 2024Observational
- A rapid host-protein test for differentiating bacterial from viral infection: Apollo diagnostic accuracy study.Journal of the American College of Emergency Physicians open · 2024Article
- Where to start? The Irish Emergency Department Antimicrobial Discharge (EDAD) study: a multicentre, prospective cohort analysis.JAC-antimicrobial resistance · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Antibiotics are some of the most commonly prescribed drugs in the Emergency Department (ED) and yet data describing the overall appropriateness of antibiotic prescribing in the ED is scarce. Objectives: To describe the appropriateness of antibiotic prescribing in the ED. Methods: A retrospective, observational study of current practice. All patients who presented to the ED during the study period and were prescribed at least one antibiotic were included. Specialists from Infectious Disease, Microbiology and Emergency Medicine and a Senior Pharmacist assessed antibiotic appropriateness against evidence-based guidelines. Results: A total of 1019 (13.6%) of patient presentations involved the prescription of at least one antibiotic. Of these, 640 (62.8%) antibiotic prescriptions were assessed as appropriate, 333 (32.7%) were assessed as inappropriate and 46 (4.5%) were deemed to be not assessable. Adults were more likely to receive an inappropriate antibiotic prescription than children (36.9% versus 22.9%; difference 14.1%, 95% CI 7.2%-21.0%). Patients who met quick Sepsis-related Organ Failure Assessment (qSOFA) criteria were more likely to be prescribed inappropriate antibiotics (56.7% versus 36.1%; difference 20.5%, 95% CI, 2.4%-38.7%). There was no difference in the incidence of appropriate antibiotic prescribing based on patient gender, disposition (admitted/discharged), reason for antibiotic administration (treatment/prophylaxis) or time of shift (day/night). Conclusions: Inappropriate administration of antibiotics can lead to unnecessary adverse events, treatment failure and antimicrobial resistance. With over one in three antibiotic prescriptions in the ED being assessed as inappropriate, there is a pressing need to develop initiatives to improve antibiotic prescribing to prevent antibiotic-associated patient and community harms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.