ArticleGigaScience2018
Genomes of trombidid mites reveal novel predicted allergens and laterally transferred genes associated with secondary metabolism.
Article in GigaScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Scrub typhus ecology: a systematic review of Orientia in vectors and hosts.Parasites & vectors · 2019Pooled it
- Molecular species delimitation analysis of Leptotrombidium spp. and other chigger species parasitizing birds in Malaysia.Journal of medical entomology · 2025Article
- Article
- The evolutionary history and timeline of mites in ancient soils.Scientific reports · 2025Article
- Canonical terpene synthases in arthropods: Intraphylum gene transfer.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Microbiome and mitogenomics of the chigger mite Pentidionis agamae: potential role as an Orientia vector and associations with divergent clades of Wolbachia and Borrelia.BMC genomics · 2024Article
- Multi-Locus Sequence Analysis Indicates Potential Cryptic Speciation in the Chigger MiteAnimals : an open access journal from MDPI · 2024Article
- The highly improved genome ofLife science alliance · 2023Article
- Horizontal Gene Transfer and Fusion Spread Carotenogenesis Among Diverse Heterotrophic Protists.Genome biology and evolution · 2023Article
- The redlegged earth mite draft genome provides new insights into pesticide resistance evolution and demography in its invasive Australian range.Journal of evolutionary biology · 2023Article
- Biology, Systematics, Microbiome, Pathogen Transmission and Control of Chiggers (Acari: Trombiculidae, Leeuwenhoekiidae) with Emphasis on the United States.International journal of environmental research and public health · 2022Review
- Human follicular mites: Ectoparasites becoming symbionts.Molecular biology and evolution · 2022Article
- Functional Characterization of Non-Ankyrin Repeat Domains of Orientia tsutsugamushi Ank Effectors Reveals Their Importance for Molecular Pathogenesis.Infection and immunity · 2022Article
- Establishment of a Rhesus Macaque Model for Scrub Typhus Transmission: Pilot Study to Evaluate the MinimalPathogens (Basel, Switzerland) · 2021Article
- Targeted capture and sequencing of Orientia tsutsugamushi genomes from chiggers and humans.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Article
- Comparative analysis of mite genomes reveals positive selection for diet adaptation.Communications biology · 2021Article
- Transcriptomic analysis of the poultry red mite, Dermanyssus gallinae, across all stages of the lifecycle.BMC genomics · 2021Article
- A Highly Contiguous Genome Assembly of a Polyphagous Predatory Mite Stratiolaelaps scimitus (Womersley) (Acari: Laelapidae).Genome biology and evolution · 2021Article
- Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand.Animal microbiome · 2019Article
- Convergent evolution of cytochrome P450s underlies independent origins of keto-carotenoid pigmentation in animals.Proceedings. Biological sciences · 2019Article
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Trombidid mites have a unique life cycle in which only the larval stage is ectoparasitic. In the superfamily Trombiculoidea ("chiggers"), the larvae feed preferentially on vertebrates, including humans. Species in the genus Leptotrombidium are vectors of a potentially fatal bacterial infection, scrub typhus, that affects 1 million people annually. Moreover, chiggers can cause pruritic dermatitis (trombiculiasis) in humans and domesticated animals. In the Trombidioidea (velvet mites), the larvae feed on other arthropods and are potential biological control agents for agricultural pests. Here, we present the first trombidid mites genomes, obtained both for a chigger, Leptotrombidium deliense, and for a velvet mite, Dinothrombium tinctorium. Results: Sequencing was performed using Illumina technology. A 180 Mb draft assembly for D. tinctorium was generated from two paired-end and one mate-pair library using a single adult specimen. For L. deliense, a lower-coverage draft assembly (117 Mb) was obtained using pooled, engorged larvae with a single paired-end library. Remarkably, both genomes exhibited evidence of ancient lateral gene transfer from soil-derived bacteria or fungi. The transferred genes confer functions that are rare in animals, including terpene and carotenoid synthesis. Thirty-seven allergenic protein families were predicted in the L. deliense genome, of which nine were unique. Preliminary proteomic analyses identified several of these putative allergens in larvae. Conclusions: Trombidid mite genomes appear to be more dynamic than those of other acariform mites. A priority for future research is to determine the biological function of terpene synthesis in this taxon and its potential for exploitation in disease control.
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