ReviewJournal of animal science2018
BOARD-INVITED REVIEW: Arginine nutrition and metabolism in growing, gestating, and lactating swine.
Review in Journal of animal science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
51 citing papers in PubMed, 65 citations in OpenAlex.
- Effect of Berberine on Improving Reproduction Disorder in Female Mice with Type 2 Diabetes Mellitus.Chinese journal of integrative medicine · 2026Article
- Effects of Ad Libitum Feeding and Arginine Supplementation on Growth of Piglets and Reproductive Performance Parameters of Sows.Animals : an open access journal from MDPI · 2026Article
- Multifaceted effects of proline on intestinal injury, inflammation, and lipid metabolism in piglets induced by porcine epidemic diarrhea virus.Amino acids · 2026Article
- Influence of sire fertility on the metabolism of in vitro produced embryos.Reproduction & fertility · 2026Article
- The effects of citrulline on horse milk components and fecal metabolism were analyzed based on LC-MS and 16s amplicon.BMC veterinary research · 2026Article
- Enhancement of growth performance, intestinal morphology, plasma biomarkers, and hepatic metabolomics in broiler chickens through medicinal plants-seaweed blend supplementation in drinking water.Journal of animal science · 2026Article
- Nutrient assessment of sea buckthorn residues as potential feed ingredients.Frontiers in veterinary science · 2026Article
- Dietary arginine-to-lysine ratio influences nutrient digestibility during early growth without affecting growth performance in growing-finishing pigs.Frontiers in veterinary science · 2026Article
- Article
- Novel Aspects of the Physiology of Pregnancy in Domestic Ruminants.Animals : an open access journal from MDPI · 2025Review
- Dietary Arginine Supplementation Modulates the Proteome of Boar Seminal Plasma.Animals : an open access journal from MDPI · 2025Article
- Oral Administration of L-Arginine Improves the Growth and Survival of Sow-Reared Intrauterine Growth-Restricted Piglets.Animals : an open access journal from MDPI · 2025Article
- Effect of supplementation withFrontiers in microbiology · 2025Article
- Productive and metabolomic consequences of arginine supplementation in sows during different gestation periods in two different seasons.Journal of animal science and biotechnology · 2024Article
- Effect of standardized ileal digestible arginine:lysine on growth performance of 6- to 13-kg nursery pigs.Journal of animal science · 2024Article
- Safety of dietary nitrate supplementation by calcium nitrate for finishing pigs as measured by methemoglobin and serum and tissue nitrate levels.Translational animal science · 2024Article
- Research progress on anti-stress nutrition strategies in swine.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Review
- PlasmaScientific reports · 2023Article
- Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- Sow Nutrition, Uterine Contractions, and Placental Blood Flow during the Peri-Partum Period and Short-Term Effects on Offspring: A Review.Animals : an open access journal from MDPI · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arginine (Arg) has traditionally not been considered as a deficient nutrient in diets for gestating or lactating swine due to the assumption that these animals can synthesize sufficient amounts of Arg to meet their physiological needs. The lack of full knowledge about Arg nutrition has contributed to suboptimal efficiency of pork production. Over the past 25 yr, there has been growing interest in Arg metabolism in the pig, which is an agriculturally important species and a useful model for studying human biology. Arginine is a highly abundant amino acid in tissues of pigs, a major amino acid in allantoic fluid, and a key regulator of gene expression, cell signaling, and antioxidative reactions. Emerging evidence suggests that dietary supplementation with 0.5% to 1% Arg maintains gut health and prevents intestinal dysfunction in weanling piglets, while enhancing their growth performance and survival. Also, the inclusion of 1% Arg in diets is required to maximize skeletal muscle accretion and feed efficiency in growing pigs, whereas dietary supplementation with 1% Arg reduces muscle loss in endotoxin-challenged pigs. Furthermore, supplementing 0.83% Arg to corn- and soybean meal-based diets promotes embryonic/fetal survival in swine and milk production by lactating sows. Thus, an adequate amount of dietary Arg as a quantitatively major nutrient is necessary to support maximum growth, lactation, and reproduction performance of swine. These results also have important implications for improving the nutrition and health of humans and other animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.