Evidence map›Paper›PMID 30445390›Full record

ArticleJournal of affective disorders2019

Family functioning, trauma exposure and PTSD: A cross sectional study.

Sarah Dorrington, Helena Zavos, Harriet Ball, Peter McGuffin, Athula Sumathipala, Sisira Siribaddana, Fruhling Rijsdijk, Stephani L Hatch, Matthew Hotopf

Abstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah DorringtonDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; South London and Maudsley NHS Foundation Trust, UK.
Helena ZavosDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Harriet BallNorth Bristol NHS Trust, Bristol, UK.
Peter McGuffinMRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Athula SumathipalaDepartment of Primary Care and Health Services, Keele University, Staffordshire, UK.
Sisira SiribaddanaFaculty of Medicine & Allied Science, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka.
Fruhling RijsdijkMRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Stephani L HatchDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Matthew HotopfDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; South London and Maudsley NHS Foundation Trust, UK. Electronic address: matthew.hotopf@kcl.ac.uk.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveOnly a minority of trauma-exposed individuals go on to develop post traumatic stress disorder (PTSD). Previous studies in high income countries suggest that maladaptive family functioning adversities (MFFA) in childhood may partially explain individual variation in vulnerability to PTSD following trauma. We test in a lower middle-income setting (Sri Lanka) whether: (1) MFFA is associated with trauma exposure; (2) MFFA moderates the association between exposure to trauma and later (a) PTSD (b) other psychiatric diagnoses; and (3) any association between MFFA and PTSD is explained by experiences of interpersonal violence, cumulative trauma exposure or comorbid psychopathology.

methodsWe conducted a population study of 3995 twins and 2019 singletons residing in Colombo, Sri Lanka. Participants completed the Composite International Diagnostic Interview, including nine traumatic exposures and a questionnaire on MFFA.

results23.4% of participants reported exposure to MFFA. We found that (1) MFFA was strongly associated with trauma exposure (2) MFFA moderates the association between trauma exposure and both (a) PTSD and (b) other DSM psychiatric diagnosis. (3) This was not explained by interpersonal violence, cumulative trauma exposure or other psychopathology.

conclusionsMFFA moderates the association between trauma and PTSD, and the association between trauma and non-PTSD psychopathology.

Indexed as

AdolescentAdultChildComorbidityCross-Sectional StudiesExposure to ViolenceFamily RelationsFemaleHumansMaleMiddle AgedPovertySri LankaStress Disorders, Post-TraumaticSurveys and QuestionnairesTwins

Identifiers

PMID30445390
PMCPMC6362264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.