Evidence map›Paper›PMID 30445272›Full record

Trial reportDrug and alcohol dependence2019

An intervention trial targeting methadone maintenance treatment providers to improve clients' treatment retention in China.

Li Li, Zunyou Wu, Li-Jung Liang, Chunqing Lin, Sitong Luo, Xiaobin Cao, Julie Hsieh, Keming Rou

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Li LiSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA. Electronic address: lililili@ucla.edu.
Zunyou WuNational Center for AIDS/STD Control and Prevention, Chinese Centers for Disease Control and Prevention, Beijing, China.
Li-Jung LiangSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Chunqing LinSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Sitong LuoSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Xiaobin CaoNational Center for AIDS/STD Control and Prevention, Chinese Centers for Disease Control and Prevention, Beijing, China.
Julie HsiehSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Keming RouNational Center for AIDS/STD Control and Prevention, Chinese Centers for Disease Control and Prevention, Beijing, China.
University of California, Los Angeles · US

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
MMT CARE For HIV Prevention: A Randomized Controlled TrialR01DA033130 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, LI · 2012 to 2016
$3.0M
UCLA/China CDC Training Program in Advanced Research MethodologiesD43TW009586 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DETELS, ROGER, LI, LI · 2013 to 2017
$1.2M
FIC NIH HHS D43 TW009586NIDA NIH HHS R01 DA033130NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundService providers including doctors, nurses, and other healthcare professionals play an essential role in methadone maintenance treatment (MMT). This study evaluated the impact of an intervention targeting MMT providers on their clients' treatment retention.

methodsThis study was conducted in 68 MMT clinics in five provinces of China with 36 clients randomly selected from each clinic. The clinics were randomized to intervention or control condition. The MMT CARE intervention started with group sessions to enhance providers' communication skills. The trained providers were encouraged to conduct individual sessions with clients to promote treatment engagement. The outcomes, which include client retention (main outcome) and their reception of provider-delivered individual sessions (process outcome), were measured over a 24-month period.

resultsSignificantly fewer intervention clients dropped out from MMT than control clients during the study period (31% vs. 41%; p < 0.0001). Dropout hazard was significantly lower in the intervention condition compared to the control condition (HR = 0.71, 95% CI: 0.57, 0.89). More intervention clients had individual sessions than control clients (93% vs. 70%; p < 0.0001). Having individual sessions was associated with a significantly lower dropout hazard (HR = 0.30, 95% CI: 0.23, 0.40). The intervention clients had a significantly lower dropout hazard than the control clients if they started the individual sessions during the first six months (HR = 0.68, 95% CI: 0.51, 0.90).

conclusionsThe MMT CARE intervention focusing on provider capacity building has demonstrated efficacy in reducing clients' treatment dropout. This study sheds light on MMT service improvement in China and other global community-based harm reduction programs.

Indexed as

AdultAmbulatory Care FacilitiesAnalgesics, OpioidChinaFemaleFollow-Up StudiesHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentPatient DropoutsRetention in CareTreatment OutcomeAnalgesics, OpioidMethadoneMethadone maintenance treatmentRandomized controlled trialService providersTreatment retention

Identifiers

PMID30445272
PMCPMC6413495
OpenAlexW2898109355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.