Evidence map›Paper›PMID 30444344›Full record

ArticleACS applied materials & interfaces2018

Implanted Battery-Free Direct-Current Micro-Power Supply from in Vivo Breath Energy Harvesting.

Jun Li, Lei Kang, Yin Long, Hao Wei, Yanhao Yu, Yizhan Wang, Carolina A Ferreira, Guang Yao, Ziyi Zhang, Corey Carlos and 4 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 70 citations in OpenAlex.

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  16. Review
  17. Wearable and Implantable Electroceuticals for Therapeutic Electrostimulations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  18. Review
  19. Review
  20. Degradable Piezoelectric Biomaterials for Wearable and Implantable Bioelectronics.Current opinion in solid state & materials science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Jun LiDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.ORCID http://orcid.org/0000-0002-7498-6736
Lei KangDepartment of Radiology and Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Yin LongDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Hao WeiDepartment of Radiology and Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Yanhao YuDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Yizhan WangDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Carolina A FerreiraDepartment of Radiology and Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Guang YaoDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Ziyi ZhangDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Corey CarlosDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Lazarus GermanDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.
Xiaoli LanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College , Huazhong University of Science and Technology , Wuhan 430022 , China.
Weibo CaiDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.ORCID http://orcid.org/0000-0003-4641-0833
Xudong WangDepartment of Materials Science and Engineering , University of Wisconsin-Madison , Madison , Wisconsin 53706 , United States.ORCID http://orcid.org/0000-0002-9762-6792
University of Wisconsin–Madison · USUnion Hospital · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Membranous Nanogenerators for in vivo Bio-mechanical Energy HarvestingR01EB021336 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2016 to 2020
$1.7M
NCI NIH HHS P30 CA014520NIBIB NIH HHS R01 EB021336
6 · The paper itself

Abstract

In vivo biomechanical energy harvesting by implanted nanogenerators (i-NGs) is promising for self-powered implantable medical devices (IMDs). One critical challenge to reach practical applications is the requirement of continuous direct-current (dc) output, while the low-frequency body activities typically generate discrete electrical pulses. Here, we developed an ultrastretchable micrograting i-NG system that could function as a battery-free dc micro-power supply. Packaged by a soft silicone elastomer with a cavity design, the i-NG exhibited an ultralow Young's modulus of ∼45 kPa and a high biocompatibility to soft biological tissues. The i-NG was implanted inside the abdominal cavity of Sprague Dawley adult rats and directly converted the slow diaphragm movement during normal respiration into a high-frequency alternative current electrical output, which was readily transmitted into a continuous ∼2.2 V dc output after being integrated with a basic electrical circuit. A light-emitting diode was constantly operated by the breath-driven i-NG without the aid of any battery component. This solely biomechanical energy-driven dc micro-power supply offers a promising solution for the development of self-powered IMDs.

Indexed as

Bioelectric Energy SourcesEquipment DesignRespiratory Mechanics3T3 CellsAnimalsMiceRatsRats, Sprague-Dawleybattery-free systemdirect-current micro-power sourceenergy harvesting from respirationimplantable medical devicesimplantable nanogenerator

Identifiers

PMID30444344
PMCPMC6456428
OpenAlexW2901917366

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.