Evidence map›Paper›PMID 30444264›Full record

ArticleThe Laryngoscope2019

Voice therapy associated with a decrease in the reflux symptoms index in patients with voice complaints.

Sarah L Schneider, Matthew S Clary, Daniel Steven Fink, Sean X Wang, Farshad N Chowdhury, Rena Yadlapati, Marie E Jetté, Mark S Courey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Validation of the Laryngeal Cognitive-Affective Tool.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  5. Voice Hoarseness with Reflux as a Suspected Etiology: Incidence, Evaluation, Treatment, and Symptom Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah L SchneiderDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.
Matthew S ClaryDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Daniel Steven FinkDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Sean X WangSutter Health, Fremont, California.
Farshad N ChowdhuryDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Rena YadlapatiDivision of Gastroenterology and Hepatology, University of Colorado School of Medicine, Aurora, Colorado.
Marie E JettéDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Mark S CoureyDepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai Health System, New York, New York, U.S.A.

Funding

Targeting Hypervigilance and Autonomic Arousal: the Psycho-physiologic Model of GERDR01DK092217 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JOHN E PANDOLFINO · 2012 to 2026
$5.0M
Institutional Training in Otolaryngology ResearchT32DC012280 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI Yuri Agrawal, Sue C. Kinnamon · 2013 to 2026
$3.4M
NIDCD NIH HHS L30 DC015659NIDCD NIH HHS T32 DC012280NIDDK NIH HHS R01 DK092217
6 · The paper itself

Abstract

objectives/hypothesisPatients with muscle tension dysphonia often demonstrate an elevation in Reflux Symptom Index (RSI) and 10-item Voice Handicap Index (VHI-10) scores, and may be erroneously diagnosed with laryngopharyngeal reflux disease. In this study we assessed the effects of voice therapy on RSI and VHI-10 scores in patients with voice complaints not responsive to antireflux medications. STUDY

designRetrospective cohort study.

methodsA study of patients was conducted at a single tertiary-care center over 1 year (January 2012-January 2013). Patients were included if they had dysphonia not responsive to proton pump inhibition, did not have neurologic or neoplastic disease, and participated in at least three voice-therapy sessions in the absence of antireflux therapy. Primary analysis assessed change in RSI scores between the initial and follow-up visits with a laryngologist.

resultsA total of 18 patients were included (mean age = 49.9 ± 14.5 years, 89% female, 83% with a primary complaint of dysphonia). From initial to follow-up visit, the median RSI score (18.5 [interquartile range {IQR}, 9.5-22.8] vs. 10.5 [IQR, 4.5-14]; P = .02) and median VHI-10 score (25.5 [IQR, 11.3-30.0] vs. 13.5 [IQR, 9.5-20.8]; P = .03) significantly decreased. A significant inverse correlation was found between the number of voice therapy sessions/month and change in RSI score (r = -0.4; P = .05).

conclusionsIn this study of patients with muscle tension dysphonia or vocal hyperfunction not responsive to antireflux therapy, RSI and VHI-10 scores improved following voice therapy. Results suggest that self-reported symptoms typically attributed to laryngopharyngeal reflux disease may actually be secondary to inefficient voice use patterns or anxiety about dysphonia that are responsive to voice therapy. LEVEL OF EVIDENCE: 4 Laryngoscope, 129:1169-1173, 2019.

Indexed as

Voice TrainingCohort StudiesDysphoniaFemaleHumansLaryngopharyngeal RefluxMaleMiddle AgedRetrospective StudiesSymptom Assessmentlaryngopharyngeal refluxMuscle tension dysphoniareflux symptom index

Identifiers

PMID30444264
PMCPMC6529330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.