Evidence map›Paper›PMID 30444190›Full record

ReviewTechnology in cancer research & treatment2018

MicroRNA Regulation of Energy Metabolism to Induce Chemoresistance in Cancers.

Jin Ye, Manman Zou, Pei Li, Hui Liu

Open access · goldAbstract readReview
In one paragraph

Review in Technology in cancer research & treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jin Ye1 The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Manman Zou1 The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Pei Li1 The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Hui Liu1 The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.ORCID 0000-0002-0912-4216
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresistance has been probed recently. In this review, we summarize 5 microRNAs in regulating glucose and lipid metabolism and other energy metabolism. They partially modulate chemoresistance to cancer treatments. Furthermore, we discuss the great therapeutic potential of metabolism-related microRNAs in novel combinatorial means to treat human cancers.

Indexed as

AnimalsAntineoplastic AgentsBiomarkers, TumorCell Line, TumorDrug Resistance, NeoplasmEnergy MetabolismGene Expression Regulation, NeoplasticHumansMicroRNAsNeoplasmsAntineoplastic AgentsBiomarkers, TumorMicroRNAsantineoplastic agentscarcinomadrug resistanceenergy metabolismmicroRNAs

Identifiers

PMID30444190
PMCPMC6243412
OpenAlexW2900616687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.