Evidence map›Paper›PMID 30444143›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2019

The leaky lung test: a pilot study using inhaled mannitol to measure airway barrier function in asthma.

Steve Georas, Nicole Ransom, Sara Hillman, Sophia Eliseeva, Janelle Veazey, Timothy Smyth, Kim Le, Jon Meddings

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Epithelial barriers in allergy and asthma.The Journal of allergy and clinical immunology · 2020
    Review
  4. Humoral First-Line Mucosal Innate Defence in vivo.Journal of innate immunity · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Steve GeorasDepartment of Medicine, University of Rochester Medical Center , Rochester, NY , USA.
Nicole RansomDepartment of Medicine, University of Rochester Medical Center , Rochester, NY , USA.
Sara HillmanDepartment of Medicine, University of Rochester Medical Center , Rochester, NY , USA.
Sophia EliseevaDepartment of Medicine, University of Rochester Medical Center , Rochester, NY , USA.
Janelle VeazeyDepartment of Microbiology & Immunology, University of Rochester Medical Center , Rochester, NY , USA.
Timothy SmythDepartment of Environmental Health Sciences, University of Rochester Medical Center , Rochester, NY , USA.
Kim LeCumming School of Medicine, University of Calgary , Calgary , Alberta.
Jon MeddingsCumming School of Medicine, University of Calgary , Calgary , Alberta.
University of Rochester Medical Center · USUniversity of Calgary · CA

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Steve N Georas · 1985 to 2026
$42.8M
Training in Environment ToxicologyT32ES007026 · NIEHS · UNIVERSITY OF ROCHESTER · PI Alison Elder, Marissa Sobolewski Terry · 1985 to 2026
$20.2M
MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
The T32 Predoctoral Training Program in Immunology (PTPI)T32AI007285 · NIAID · UNIVERSITY OF ROCHESTER · PI Scott Andrew Gerber, JACQUES Robert · 1986 to 2026
$7.6M
EPITHELIAL BARRIER DYSFUNCTION AND MUCOSAL INFLAMMATION IN ASTHMAR01HL122424 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N · 2014 to 2017
$1.9M
New role for (airway) epithelial PKD in anti-viral immunityF31HL140795 · NHLBI · UNIVERSITY OF ROCHESTER · PI VEAZEY, JANELLE MARIE · 2018 to 2020
$112k
Mechanisms of Endotoxin-induced Breakdown of Tolerance in the LungF32HL110718 · NHLBI · UNIVERSITY OF ROCHESTER · PI CHAPMAN, TIMOTHY J. · 2011 to 2013
$102k
NHLBI NIH HHS F31 HL140795NHLBI NIH HHS F32 HL110718NHLBI NIH HHS R01 HL122424NHLBI NIH HHS T32 HL066988NIAID NIH HHS T32 AI007285NIEHS NIH HHS P30 ES001247NIEHS NIH HHS T32 ES007026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationAirway ManagementAirway RemodelingAnalysis of VarianceAnti-Asthmatic AgentsArea Under CurveAsthmaBronchial Provocation TestsCase-Control StudiesDose-Response Relationship, DrugDrug Administration ScheduleEpitheliumFemaleForced Expiratory VolumeHumansLungAnti-Asthmatic AgentsMannitolairway epithelial cellairway inflammationAsthmaepithelial barrier dysfunctiontight junction

Identifiers

PMID30444143
PMCPMC6522330
OpenAlexW2900975513

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.