ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2019
Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Predictive Performance and Rater Reliability of CT-derived Virtual Reality Models for PDA Stent Planning in Patients with Ductal-Dependent Cyanotic Congenital Heart Disease.Pediatric cardiology · 2026Article
- Artificial intelligence, extended reality and computational modelling in cross-sectional cardiovascular imaging in congenital heart disease: a narrative review.Cardiovascular diagnosis and therapy · 2026Review
- Article
- Valve Frame Geometry and Arrhythmia Risk Following Self-Expanding Transcatheter Pulmonary Valve Replacement.Pediatric cardiology · 2026Article
- Article
- Quantitative Analysis of 3D Anatomy to Inform Planning of Ductal Arteriosus Stenting.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- 4-Dimensional Right Ventricular Outflow Tract Segmentation to Evaluate Candidacy for Transcatheter Pulmonary Valve Replacement.Pediatric cardiology · 2025Article
- HVSMR-2.0: A 3D cardiovascular MR dataset for whole-heart segmentation in congenital heart disease.Scientific data · 2024Article
- Novel Techniques in Imaging Congenital Heart Disease: JACC Scientific Statement.Journal of the American College of Cardiology · 2024Review
- CMR and Percutaneous Treatment of Pulmonary Regurgitation: Outreach the Search for the Best Candidate.Life (Basel, Switzerland) · 2023Review
- Clinical 3D modeling to guide pediatric cardiothoracic surgery and intervention using 3D printed anatomic models, computer aided design and virtual reality.3D printing in medicine · 2022Article
- SlicerHeart: An open-source computing platform for cardiac image analysis and modeling.Frontiers in cardiovascular medicine · 2022Review
- Single-Barrel, Double-Barrel, and Fenestrated Endografts to Facilitate Transcatheter Pulmonary Valve Replacement in Large RVOT.JACC. Cardiovascular interventions · 2020Article
- Successful integration of a three-dimensional transthoracic echocardiography-derived model with an electroanatomic mapping system to guide catheter ablation of WPW.Journal of cardiovascular electrophysiology · 2020Article
- Simulation of Transcatheter Atrial and Ventricular Septal Defect Device Closure Within Three-Dimensional Echocardiography-Derived Heart Models on Screen and in Virtual Reality.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2020Article
- Personalized Interventions: A Reality in the Next 20 Years or Pie in the Sky.Pediatric cardiology · 2020Review
- Quest for cardiovascular interventions: precise modeling and 3D printing of heart valves.Journal of biological engineering · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundPulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter-based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). We sought to quantify the differences in compression and volume for actual implants, and those predicted by pre-implant modeling.
methodsWe used custom software to interactively place virtual transcatheter pulmonary valves (TPVs) into RVOT models created from pre-implant and post Harmony valve implant CT scans of 5 ovine surgical models of TOF to quantify and visualize device volume and compression.
resultsVirtual device placement visually mimicked actual device placement and allowed for quantification of device volume and radius. On average, simulated proximal and distal device volumes and compression did not vary statistically throughout the cardiac cycle (P = 0.11) but assessment was limited by small sample size. In comparison to actual implants, there was no significant pairwise difference in the proximal third of the device (P > 0.80), but the simulated distal device volume was significantly underestimated relative to actual device implant volume (P = 0.06).
conclusionsThis study demonstrates that pre-implant modeling which assumes a rigid vessel wall may not accurately predict the degree of distal RVOT expansion following actual device placement. We suggest the potential for virtual modeling of TPVR to be a useful adjunct to procedural planning, but further development is needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.