Evidence map›Paper›PMID 30443929›Full record

ArticleMagnetic resonance in medicine2019

Motion-robust diffusion compartment imaging using simultaneous multi-slice acquisition.

Bahram Marami, Benoit Scherrer, Shadab Khan, Onur Afacan, Sanjay P Prabhu, Mustafa Sahin, Simon K Warfield, Ali Gholipour

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Bahram MaramiDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Benoit ScherrerDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Shadab KhanDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Onur AfacanDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Sanjay P PrabhuDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Mustafa SahinHarvard Medical School, Boston, Massachusetts.
Simon K WarfieldDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Ali GholipourDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.

Funding

Toward better characterization and clinical trial readiness for targeting neuropsychiatric manifestations in PTEN pathogenic variantsU54NS092090 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI MUSTAFA SAHIN · 2014 to 2026
$20.1M
Early Biomarkers of Autism Spectrum Disorders in infants with Tuberous SclerosisU01NS082320 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI KRUEGER, DARCY, SAHIN, MUSTAFA · 2012 to 2018
$13.3M
Improved Motion Robust MRI of ChildrenR01EB019483 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2015 to 2024
$3.9M
MRI Biomarkers of Patients with Tuberous Sclerosis Complex and AutismR01NS079788 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2013 to 2017
$3.6M
Motion-robust super-resolution diffusion weighted MRI of early brain developmentR01EB018988 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI GHOLIPOUR-BABOLI, ALI · 2014 to 2017
$1.6M
NIBIB NIH HHS R01 EB018988NIBIB NIH HHS R01 EB019483NINDS NIH HHS R01 NS079788NINDS NIH HHS U01 NS082320NINDS NIH HHS U54 NS092090
6 · The paper itself

Abstract

purposeTo achieve motion-robust diffusion compartment imaging (DCI) in near continuously moving subjects based on simultaneous multi-slice, diffusion-weighted brain MRI.

methodsSimultaneous multi-slice (SMS) acquisition enables fast and dense sampling of k- and q-space. We propose to achieve motion-robust DCI via slice-level motion correction by exploiting the rigid coupling between simultaneously acquired slices. This coupling provides 3D coverage of the anatomy that substantially constraints the slice-to-volume alignment problem. This is incorporated into an explicit model of motion dynamics that handles continuous and large subject motion in robust DCI reconstruction.

resultsWe applied the proposed technique, called Motion Tracking based on Simultanous Multislice Registration (MT-SMR) to multi b-value SMS diffusion-weighted brain MRI of healthy volunteers and motion-corrupted scans of 20 pediatric subjects. Quantitative and qualitative evaluation based on fractional anisotropy in unidirectional fiber regions, and DCI in crossing-fiber regions show robust reconstruction in the presence of motion.

conclusionThe proposed approach has the potential to extend routine use of SMS DCI in very challenging populations, such as young children, newborns, and non-cooperative patients.

Indexed as

Diffusion Magnetic Resonance ImagingAdolescentAdultAlgorithmsAnisotropyBrainChildChild, PreschoolHealthy VolunteersHumansImage Processing, Computer-AssistedImaging, Three-DimensionalModels, StatisticalMotionReproducibility of ResultsDiffusion-compartment imagingdiffusion-weighted MRIimage-based navigationintra-volume motionmotion-robustmotion trackingsimultaneous multi-sliceslice registration

Identifiers

PMID30443929
PMCPMC6414287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.