Evidence map›Paper›PMID 30443851›Full record

ArticleFunctional & integrative genomics2019

Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress.

Min Zhou, Shigang Zheng, Rong Liu, Jing Lu, Lu Lu, Chihong Zhang, Zehou Liu, Congpei Luo, Lei Zhang, Yu Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Functional & integrative genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Physio-biochemical and transcriptomic analysis reveals underlying mechanism of Cys-induced amelioration of Cd toxicity in maize.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  3. Review
  4. Article
  5. Multi-Omics Uncover the Mechanism of Wheat under Heavy Metal Stress.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Min ZhouChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Shigang ZhengChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Rong LiuChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Jing LuChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Lu LuChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Chihong ZhangChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Zehou LiuChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Congpei LuoChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China.
Lei ZhangChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China. zhanglei_7810@163.com.
Yu WuChengdu Institute of Biology, Chinese Academy of Sciences, No.9, section 4 of South RenMin Road, Wuhou District, Chengdu, 610041, Sichuan, China. wuyugood@126.com.
Chinese Academy of Sciences · CNChengdu Institute of Biology · CNUniversity of Chinese Academy of Sciences · CN

Funding

the "13th Five-year Plan" for National Key Research and Develop Grant No. 2016YFD0102000
6 · The paper itself

Abstract

Wheat, one of the most broadly cultivated and consumed food crops worldwide, can accumulate high Cd contents in their edible parts, which poses a major hazard to human health. Cd accumulation ability differs among varieties in wheat, but the underlying molecular mechanism is largely unknown. Here, key genes responsible for Cd accumulation between two contrasting wheat genotypes (low-Cd accumulation one L17, high-Cd accumulation one H17) were investigated. Total 1269 were differentially expressed genes (DEGs) in L17 after Cd treatment, whereas, 399 Cd-induced DEGs were found in H17. GO-GO network analysis showed that heme binding was the most active GO, and metal binding was the second one that associated with other GOs in response to Cd stress in both genotypes. Pathway-pathway network analysis showed that phenylpronanoid biosynthesis and glutathione metabolism were the top pathways in response to Cd stress in both genotypes. Furthermore, we found that DEGs related to ion binding, antioxidant defense mechanisms, sulfotransferase activity, and cysteine biosynthetic process were more enriched in L17. In conclusion, our results not only provide the foundation for further exploring the molecular mechanism of Cd accumulation in wheat but also supply new strategies for improving phytoremediation ability of wheat by genetic engineering.

Indexed as

Stress, PhysiologicalTranscriptomeCadmiumGenotypePlant RootsTriticumCadmiumCadmiumGO-GO networkPathway-pathway networkRNA sequencingWheat

Identifiers

PMID30443851
OpenAlexW2900550802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.