Evidence map›Paper›PMID 30443844›Full record

ArticlePathology oncology research : POR2020

The Gene Mutation Spectrum of Breast Cancer Analyzed by Semiconductor Sequencing Platform.

Yanhui Liu, Bo Yang, Xiaoyan Zhang, Quanfei Huang, Hailiang Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Pathology oncology research : POR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanhui LiuDongguan Institute of Reproductive and Genetic Research, Dongguan Maternal and Child Health Hospital, Dongguan, 523000, Guangdong, China. liuliang71215@163.com.
Bo YangDongguan Institute of Reproductive and Genetic Research, Dongguan Maternal and Child Health Hospital, Dongguan, 523000, Guangdong, China.
Xiaoyan ZhangDongguan Institute of Reproductive and Genetic Research, Dongguan Maternal and Child Health Hospital, Dongguan, 523000, Guangdong, China.
Quanfei HuangCapitalBio Technology Inc., Beijing, 101111, China.
Hailiang LiuCapitalBio Technology Inc., Beijing, 101111, China. hlliu@capitalbiotech.com.
Dongguan People’s Hospital · CN

Funding

Dongguan City Social Science and Technology Development Project 2015108101030
6 · The paper itself

Abstract

To use the semiconductor sequencing platform (SSP) to analyze the gene mutate spectrum of breast cancer patients. We recruited 46 breast cancer patients, and detected the ER/PR/HER2 expression level of the tumor tissue by immunohistochemistry. In addition, combined with SSP technology, we detected 207 hot mutation regions of 50 breast cancer related genes with multiple polymerase chain reaction (PCR) technology. There were 8 cases of grade I, 18 cases of grade II, 20 cases of grade III in 46 breast cancer patients according to histological grade and 12 cases of ER/PR

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsDNA Mutational AnalysisFemaleHigh-Throughput Nucleotide SequencingHumansMiddle AgedSemiconductorsSequence Analysis, DNABreast cancerGenetic screeningMutate spectrumSemiconductor sequencing platform (SSP)

Identifiers

PMID30443844
OpenAlexW2901229043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.