Evidence map›Paper›PMID 30443825›Full record

ArticleMolecular biology reports2019

Nonadditive expression of lipid metabolism pathway-related genes in intestine of hybrids of Nile tilapia females (Oreochromis niloticus) and blue tilapia males (Oreochromis aureus).

Yi Zhou, Xiaojin Zhang, Qian Xu, Jinpeng Yan, Fan Yu, Jun Xiao, Zhongbao Guo, Yongju Luo, Huan Zhong

Abstract read
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Article in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Integration of mRNA and miRNA Profiling Reveals Heterosis inAnimals : an open access journal from MDPI · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi ZhouGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China.
Xiaojin ZhangGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China.
Qian XuDepartment of Cell Biology, School of Life Sciences, Central South University, Changsha, 410017, China.
Jinpeng YanDepartment of Cell Biology, School of Life Sciences, Central South University, Changsha, 410017, China.
Fan YuLaboratory of Freshwater Fisheries and Germplasm Resources Utilization, Freshwater Fisheries Research Center, Ministry of Agriculture, Chinese Academy of Fishery Sciences, Wuxi, 214081, China.
Jun XiaoGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China.
Zhongbao GuoGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China.
Yongju LuoGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China.
Huan ZhongGuangxi Tilapia Genetic Breeding Center, Guangxi Academy of Fishery Sciences, Nanning, 530021, China. zhonghuanzh@126.com.ORCID http://orcid.org/0000-0002-8762-0282

Funding

China Agriculture Research System CARS-46National Natural Science Foundation of China 31460688National Natural Science Foundation of China 31672627National Natural Science Foundation of China 31760756Natural Science Foundation of Guangxi Province 2017GXNSFFA198001Public Welfare of Institute Research Funding in Guangxi CXIF-2016-14
6 · The paper itself

Abstract

Nonadditive expression contributes to heterosis in hybrids. In this study, the expression profiles of twelve lipid metabolism pathway-related genes were investigated in the intestine of Nile tilapia (Oreochromis niloticus) ♀ × blue tilapia (Oreochromis aureus) ♂ hybrid. The expression of genes from the hybrid were assigned to nonadditive and additive expression pattern groups and compared with expression patterns from Nile tilapia and blue tilapia. In the intestine of the hybrid, apoA4B was expressed at intermediate levels, but apoB and MTP were assigned to ELD-B and ELD-N categories, respectively. The LPL and LRP1 showed transgressive up-regulation in the hybrid, but LDLR was assigned to the ELD-B category. For fatty acid uptake related genes, only FABP11a was categorized as nonadditive expression with transgressive up-regulation, while CD36 and FABP3 were categorized as additive expression in the intestine of the hybrid. Two genes in triacylglycerol metabolism, namely, FAS and DGAT2, showed transgressive up-regulation in the hybrid. Most of the genes analyzed in the present study showed nonadditive expression (8 in 12), and five genes showed transgressive up-regulation. These results indicated that the stimulation of lipid metabolism in the hybrid compared to that of its parents. The hyperactive expression of these genes in the hybrid may be associated with the growth and lipid usage vigor.

Indexed as

Animal FeedAnimalsCichlidsFatty AcidsFemaleHybrid VigorIntestinesLipid MetabolismLipidsMaleTilapiaTranscriptomeFatty AcidsLipidsExpression patternHeterosisLipid metabolismNonadditive expressionTilapia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.