Evidence map›Paper›PMID 30443719›Full record

ArticleObesity surgery2019

National Postoperative Bariatric Surgery Outcomes in Patients with Chronic Kidney Disease and End-Stage Kidney Disease.

Jordana B Cohen, Colleen M Tewksbury, Samuel Torres Landa, Noel N Williams, Kristoffel R Dumon

Registry-linked trialAbstract read
In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04626323 (Open, Randomized, Unicenter Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04626323 phase2unknown statusnot on this mapstarted 2021, after this paper: background citation

Open, Randomized, Unicenter Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease

TypeinterventionalSponsorHospital Alemão Oswaldo CruzRan2021 to 2024Enrolled60ConditionsDiabetes Mellitus, Type 2, Kidney Disease, Chronic, Kidney InjuryArmsRoux-en-Y gastric bypass, Best medical treatment
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Guideline
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Patient and Health Care Professional Perspectives on Addressing Obesity in ESKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Gastric bypassEClinicalMedicine · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Bariatric surgery prior to transplantation and risk of early hospital re-admission, graft failure, or death following kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jordana B CohenRenal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 831 Blockley, 423 Guardian Drive, Philadelphia, PA, 19104, USA. jco@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0003-4649-079X
Colleen M TewksburyPenn Metabolic and Bariatric Surgery Program, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Samuel Torres LandaDepartment of Surgery, Oregon Health and Science University, Portland, OR, 97239, USA.
Noel N WilliamsPenn Metabolic and Bariatric Surgery Program, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Kristoffel R DumonPenn Metabolic and Bariatric Surgery Program, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
University of Pennsylvania · USOregon Health & Science University · US

Funding

Management of hypertension in obesity: Antihypertensive class effects, blood pressure control, and renal and cardiac outcomesK23HL133843 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI COHEN, JORDANA B. · 2016 to 2020
$945k
NHLBI NIH HHS K23 HL133843
6 · The paper itself

Abstract

purposeObesity is a major risk factor for end-stage kidney disease (ESKD) and is often a barrier to kidney transplantation. However, limited evidence exists evaluating postoperative bariatric surgery outcomes in patients with chronic kidney disease (CKD) and ESKD. MATERIALS AND

methodsWe performed a retrospective cohort study of patients who underwent bariatric surgery in 2015-2016 using the national Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program dataset. Propensity score matching was used to balance characteristics across patients with CKD and ESKD vs. those without CKD.

resultsThere were 323,034 patients without CKD, 1694 patients with CKD, and 925 patients with ESKD who underwent bariatric surgery. Patients with CKD and ESKD had a significantly increased risk of 30-day reoperation (CKD odds ratio [OR] 2.25 95% confidence interval [CI] 1.45-3.51; ESKD OR 3.10, 95% CI 1.72-5.61) and readmission (CKD OR 1.98, 95% CI 1.53-2.56; ESKD OR 2.97, 95% CI 2.05-4.31) compared to patients without CKD; mortality risk was elevated in patients with ESKD (OR 11.59, 95% CI 6.71-20.04) but not in those with CKD (OR 1.00, 95% CI 0.32-3.11). Rates of adverse outcomes were < 15% across all groups. There were 12, 50, and 172 deaths per 1000 person-years among patients without CKD, with CKD, and with ESKD, respectively.

conclusionPatients with CKD and ESKD experienced higher risk of postbariatric surgery complications compared to those without kidney disease, although absolute complication rates were low across all groups. CKD and ESKD should not be perceived as contraindications to bariatric surgery.

Indexed as

AdultBariatric SurgeryFemaleHumansKidney Failure, ChronicMaleMiddle AgedObesityRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsUnited StatesBariatric surgeryChronic kidney diseaseEnd-stage renal diseaseObesityWeight loss surgery

Identifiers

PMID30443719
PMCPMC6430653
OpenAlexW2901112937

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.