Evidence map›Paper›PMID 30443559›Full record

ArticleBio-protocol2013

Invadopodia Detection and Gelatin Degradation Assay.

Begoña Díaz

Abstract read
In one paragraph

Article in Bio-protocol, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  15. Kindlin-2 controls angiogenesis through modulating Notch1 signaling.Cellular and molecular life sciences : CMLS · 2023
    Article
  16. The Role of TKS5 in Chromosome Stability and Bladder Cancer Progression.International journal of molecular sciences · 2022
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Begoña DíazSignal Transduction Program, Sanford Burnham Medical Research Institute, La Jolla, CA, USA.

Funding

GENETICS OF RNA TUMOR VIRUSESR37CA017542 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI MARTIN, G STEVEN · 1990 to 2010
$4.0M
Reactive Oxygen Species and Cancer Cell InvasionR01CA129686 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI COURTNEIDGE, SARA A · 2007 to 2011
$1.8M
GENETICS OF RNA TUMOR VIRUSESR01CA017542 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI MARTIN, G STEVEN · 1985 to 2002
$1.1M
NCI NIH HHS R01 CA017542NCI NIH HHS R01 CA129686NCI NIH HHS R37 CA017542
6 · The paper itself

Abstract

This protocol is designed to quantify invadopodia formation and activity. Invadopodia are protrusive structures elaborated by cancer cells that mediate cell attachment and remodeling of the extracellular matrix. These structures contribute to the ability of cancer cells to invade and metastasize. In this protocol, both the presence of invadopodia and their activity is simultaneously assessed and quantified by a fluorescent microscopy-based assay.

Identifiers

PMID30443559
PMCPMC6233998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.