ReviewCureus2018
Differential Diagnosis and Treatment of Restless Legs Syndrome: A Literature Review.
Review in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Irritable bowel syndrome and restless legs syndrome: a narrative review of epidemiological and pathophysiological overlap.Annals of medicine and surgery (2012) · 2026Review
- Restless legs syndrome in Parkinson's disease: epidemiology, pathogenetic overlaps, and clinical management.Journal of neurology · 2025Review
- Restless Legs Syndrome in Adult Primary Care.Cureus · 2025Review
- A survey-based approach on restless legs syndrome: practices and perspectives among Italian neurologists.Journal of neurology · 2024Article
- Evaluation of quality of life and depression in family caregivers of patients with type 1 diabetes in Iran: A case-control study.SAGE open medicine · 2023Article
- Restless Legs Syndrome and the Use of Antipsychotic Medication: An Updated Literature Review.Cureus · 2022Review
- Sleep and Circadian Rhythm Disturbances in Diabetes: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Review
- Restless legs syndrome.Nature reviews. Disease primers · 2021Review
- Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature.Diabetologia · 2021Review
- Functionally selective activation of the dopamine receptor DScientific reports · 2021Article
- The Comorbidity of Migraine and Restless Legs Syndrome.Current neurology and neuroscience reports · 2019Review
- Prevalence of Restless Leg Syndrome, Associated Variables and Impact on Sleep Quality in a Cohort of Patients with Neuropsychiatric Disorders.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restless legs syndrome (RLS) is a chronic neurological disorder affecting a growing number of people. Patients describe an irresistible urge to move their lower limbs in times of immobility. Due to its vague symptoms and similarity to other disorders, it has become increasingly difficult for primary care clinicians to properly diagnose and manage RLS. As a result, patients with RLS are routinely misdiagnosed and continue their lives without proper management. This literature review examines the current understanding of the disorder, provides key points to assist clinicians in differentiating RLS from similar disorders, and explores recently updated evidence-based guidelines for the effective management of RLS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.