Evidence map›Paper›PMID 30443369›Full record

ArticleIUCrJ2018

Ruben Sanchez-Garcia, Joan Segura, David Maluenda, Jose Maria Carazo, Carlos Oscar S Sorzano

Abstract read
In one paragraph

Article in IUCrJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. AI-based methods for biomolecular structure modeling for Cryo-EM.Current opinion in structural biology · 2025
    Review
  2. GTpick: A deep neural network for Cryo-EM particle detection.Computational and structural biotechnology journal · 2025
    Article
  3. Article
  4. Article
  5. EMDB-the Electron Microscopy Data Bank.Nucleic acids research · 2024
    Review
  6. Review
  7. Review
  8. Computational methods forFrontiers in cellular and infection microbiology · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Deep Learning-Based Advances in Protein Structure Prediction.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Review
  19. Article
  20. Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.bioRxiv : the preprint server for biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruben Sanchez-GarciaBiocomputing Unit, Spanish National Center for Biotechnology, Calle Darwin 3, 28049 Madrid, Spain.ORCID https://orcid.org/0000-0001-6156-3542
Joan SeguraBiocomputing Unit, Spanish National Center for Biotechnology, Calle Darwin 3, 28049 Madrid, Spain.
David MaluendaBiocomputing Unit, Spanish National Center for Biotechnology, Calle Darwin 3, 28049 Madrid, Spain.
Jose Maria CarazoBiocomputing Unit, Spanish National Center for Biotechnology, Calle Darwin 3, 28049 Madrid, Spain.
Carlos Oscar S SorzanoBiocomputing Unit, Spanish National Center for Biotechnology, Calle Darwin 3, 28049 Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-particle cryo-electron microscopy (cryo-EM) has recently become a mainstream technique for the structural determination of macromolecules. Typical cryo-EM workflows collect hundreds of thousands of single-particle projections from thousands of micrographs using particle-picking algorithms. However, the number of false positives selected by these algorithms is large, so that a number of different 'cleaning steps' are necessary to decrease the false-positive ratio. Most commonly employed techniques for the pruning of false-positive particles are time-consuming and require user intervention. In order to overcome these limitations, a deep learning-based algorithm named

Indexed as

cryo-EMdeep learningimage processingparticle pruningthree-dimensional reconstruction

Identifiers

PMID30443369
PMCPMC6211526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.