Evidence map›Paper›PMID 30443338›Full record

ArticleInterface focus2018

Semantic information, autonomous agency and non-equilibrium statistical physics.

Artemy Kolchinsky, David H Wolpert

Abstract read
In one paragraph

Article in Interface focus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Matters of life and death in computational cell biology.NPJ systems biology and applications · 2026
    Review
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  10. If Engrams Are the Answer, What Is the Question?Advances in neurobiology · 2024
    Article
  11. Review
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  15. Cells as the first data scientists.Journal of the Royal Society, Interface · 2023
    Article
  16. Article
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  18. Article
  19. What does it mean to be an agent?Frontiers in psychology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Artemy KolchinskySanta Fe Institute, Santa Fe, NM 87501, USA.ORCID 0000-0002-3518-9208
David H WolpertSanta Fe Institute, Santa Fe, NM 87501, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shannon information theory provides various measures of so-called syntactic information, which reflect the amount of statistical correlation between systems. By contrast, the concept of 'semantic information' refers to those correlations which carry significance or 'meaning' for a given system. Semantic information plays an important role in many fields, including biology, cognitive science and philosophy, and there has been a long-standing interest in formulating a broadly applicable and formal theory of semantic information. In this paper, we introduce such a theory. We define semantic information as the syntactic information that a physical system has about its environment which is causally necessary for the system to maintain its own existence. 'Causal necessity' is defined in terms of counter-factual interventions which scramble correlations between the system and its environment, while 'maintaining existence' is defined in terms of the system's ability to keep itself in a low entropy state. We also use recent results in non-equilibrium statistical physics to analyse semantic information from a thermodynamic point of view. Our framework is grounded in the intrinsic dynamics of a system coupled to an environment, and is applicable to any physical system, living or otherwise. It leads to formal definitions of several concepts that have been intuitively understood to be related to semantic information, including 'value of information', 'semantic content' and 'agency'.

Indexed as

agencyautonomyentropyinformation theorynon-equilibriumsemantic information

Identifiers

PMID30443338
PMCPMC6227811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.