Evidence map›Paper›PMID 30443254›Full record

ArticleFrontiers in immunology2018

Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice.

Wendi A Bacon, Russell S Hamilton, Ziyi Yu, Jens Kieckbusch, Delia Hawkes, Ada M Krzak, Chris Abell, Francesco Colucci, D Stephen Charnock-Jones

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wendi A BaconDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
Russell S HamiltonCentre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom.
Ziyi YuDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.
Jens KieckbuschDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
Delia HawkesDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
Ada M KrzakDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
Chris AbellDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.
Francesco ColucciDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
D Stephen Charnock-JonesDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R008590/1Wellcome TrustWellcome Trust 200841/Z/16/Z
6 · The paper itself

Abstract

Fetal growth restriction (FGR) causes a wide variety of defects in the neonate which can lead to increased risk of heart disease, diabetes, anxiety and other disorders later in life. However, the effect of FGR on the immune system, is poorly understood. We used a well-characterized mouse model of FGR in which placental Igf-2 production is lost due to deletion of the placental specific

Indexed as

AnimalsAnimals, NewbornDisease Models, AnimalFemaleFetal Growth RetardationInsulin-Like Growth Factor IIMaleMiceMice, Inbred C57BLOrgan SizePlacentaPregnancySingle-Cell AnalysisThymus GlandInsulin-Like Growth Factor IIdevelopmental programmingDrop-Seqfetal growth restrictionsingle-cellT-cellthymus

Identifiers

PMID30443254
PMCPMC6221967
OpenAlexW2949141481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.