ArticleFrontiers in physiology2018
Hemoglobin Changes After Long-Term Intermittent Work at High Altitude.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Does intermittent exposure to high altitude increase the risk of cardiovascular disease in workers? A systematic narrative review.BMJ open · 2020Pooled it
- Combined association of genetic predisposition and healthy lifestyle with lung cancer risk: a population-based cohort study.Translational lung cancer research · 2026Article
- Hypoxia suppresses platelet activity through GPVI down-regulation but paradoxically enhances arterial thrombosis via elevated vWF.Cardiovascular research · 2026Article
- Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High-Altitude Chinese Population: A Retrospective Real-World Analysis.Journal of clinical laboratory analysis · 2026Article
- Epidemiological patterns of pulmonary hypertension at 3,658 meters: insights from a Tibet plateau retrospective study.Journal of thoracic disease · 2026Article
- Altitude hypoxia and hypoxemia: pathogenesis and management.Signal transduction and targeted therapy · 2026Review
- Cardiovascular and autonomic modulation during nighttime rest under real-world conditions in miners exposed to chronic intermittent hypoxia.Frontiers in physiology · 2026Article
- Demographics, cardiopulmonary comorbidities, laboratory data and length of hospital stay in patients with acute exacerbation of chronic obstructive pulmonary disease at high altitude: A comparative study.Experimental and therapeutic medicine · 2025Article
- Establishing altitude-based coagulation reference ranges in Western Sichuan.Scientific reports · 2025Article
- Hematological reference intervals for adult population of Debre Berhan town, North East Ethiopia.Scientific reports · 2025Article
- Data-driven identification of metabolic and cardiovascular biomarkers in high-altitude workers: a machine learning approach.Frontiers in public health · 2025Observational
- Key GenesGenes · 2024Article
- Effects of Zinc on the Right Cardiovascular Circuit in Long-Term Hypobaric Hypoxia in Wistar Rats.International journal of molecular sciences · 2023Article
- Estimated plasma volume status: association with congestion, cardiorenal syndrome and prognosis in precapillary pulmonary hypertension.Frontiers in cardiovascular medicine · 2023Article
- Article
- Healthy worker survival effect at a high-altitude mine: prospective cohort observation.Scientific reports · 2022Article
- [Retrospective analysis of clinical characteristics of patients with metabolic-associated fatty liver disease at high and low altitude areas].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Combined effect of acute altitude exposure and vigorous exercise on platelet activation.Physiological research · 2022Article
- Article
- Cardiac Adaptation to Prolonged High Altitude Migration Assessed by Speckle Tracking Echocardiography.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic high altitude hypoxia leads to an increase in red cell numbers and hemoglobin concentration. However, the effects of long-term intermittent hypoxia on hemoglobin concentration have not fully been studied. The aim of this study was to evaluate hemoglobin levels in workers commuting between an elevation of 3,800 m (2-week working shift) and lowland below 1,700 m (2 weeks of holiday). A total of 266 healthy males, aged from 20 to 69 years (mean age 45.9 ± 0.6 years), were included into this study. The duration of intermittent high altitude exposure ranged from 0 to 21 years. Any cardiac or pulmonary disorder was excluded during annual check-ups including clinical examination, clinical lab work (blood cell count, urine analysis, and biochemistry), ECG, echocardiography, and pulmonary function tests. The mean hemoglobin level in workers was 16.2 ± 0.11 g/dL. Univariate linear regression revealed an association of the hemoglobin levels with the years of exposure. Hemoglobin levels increased 0.068 g/dL [95% CI: 0.037 to 0.099,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.