ArticleFrontiers in human neuroscience2018
Within- and Between-Session Prefrontal Cortex Response to Virtual Reality Exposure Therapy for Acrophobia.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The efficacy and acceptability of exposure therapy for the treatment of post-traumatic stress disorder in children and adolescents: a systematic review and meta-analysis.BMC psychiatry · 2022Pooled it
- How Does Virtual Reality Exposure Treatment Change the Brain Function of Acrophobia Patients? A Randomized Controlled Trial.Depression and anxiety · 2025Trial
- Cortical oxygenation during exposure therapy - in situ fNIRS measurements in arachnophobia.NeuroImage. Clinical · 2020Trial
- iVR-fNIRS: studying brain functions in a fully immersive virtual environment.Neurophotonics · 2024Review
- Differences in Brain Activity and Body Movements Between Virtual Reality and Offline Exercise: Randomized Crossover Trial.JMIR serious games · 2023Article
- Use of Virtual Reality Techniques to Rehabilitate Military Veterans with Post-Traumatic Stress Disorder (Review).Sovremennye tekhnologii v meditsine · 2023Review
- Virtual Reality Aided Therapy towards Health 4.0: A Two-Decade Bibliometric Analysis.International journal of environmental research and public health · 2022Article
- Neuronal Correlates of Small Animal Phobia in Human Subjects through fMRI: The Role of the Number and Proximity of Stimuli.Life (Basel, Switzerland) · 2021Article
- Application of Near-Infrared Spectroscopy for Evidence-Based Psychotherapy.Frontiers in psychology · 2021Article
- Will virtual rehabilitation replace clinicians: a contemporary debate about technological versus human obsolescence.Journal of neuroengineering and rehabilitation · 2020Article
- Virtual Reality and Psychedelics for the Treatment of Psychiatric Disease: A Systematic Literature Review.Clinical neuropsychiatry · 2020Article
- Neuronal correlates of spider phobia in a combined fNIRS-EEG study.Scientific reports · 2020Article
- Exposure Therapy for Post-Traumatic Stress Disorder: Factors of Limited Success and Possible Alternative Treatment.Brain sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure Therapy (ET) has demonstrated its efficacy in the treatment of phobias, anxiety and Post-traumatic Stress Disorder (PTSD), however, it suffers a high drop-out rate because of too low or too high patient engagement in treatment. Virtual Reality Exposure Therapy (VRET) is comparably effective regarding symptom reduction and offers an alternative tool to facilitate engagement for avoidant participants. Neuroimaging studies have demonstrated that both ET and VRET normalize brain activity within a fear circuit. However, previous studies have employed brain imaging technology which restricts people's movement and hides their body, surroundings and therapist from view. This is at odds with the way engagement is typically controlled. We used a novel combination of neural imaging and VR technology-Functional Near-Infrared Spectroscopy (fNIRS) and Immersive Projection Technology (IPT), to avoid these limitations. Although there are a few studies that have investigated the effect of VRET on a brain function after the treatment, the present study utilized technologies which promote ecological validity to measure brain changes after VRET treatment. Furthermore, there are no studies that have measured brain activity within VRET session. In this study brain activity within the prefrontal cortex (PFC) was measured during three consecutive exposure sessions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.