Evidence map›Paper›PMID 30443008›Full record

ArticleScientific reports2018

Hybrid in vitro diffusion cell for simultaneous evaluation of hair and skin decontamination: temporal distribution of chemical contaminants.

Hazem Matar, Nevine Amer, Sneha Kansagra, Andreia Pinhal, Elliot Thomas, Scott Townend, Joanne Larner, Robert P Chilcott

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Mass Casualty Decontamination for Chemical Incidents: Research Outcomes and Future Priorities.International journal of environmental research and public health · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hazem MatarResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Nevine AmerResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Sneha KansagraResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Andreia PinhalResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Elliot ThomasResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Scott TownendResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Joanne LarnerResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK.
Robert P ChilcottResearch Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, University of Hertfordshire, Hatfield, UK. tox.publications@herts.ac.uk.
University of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most casualty or personnel decontamination studies have focused on removing contaminants from the skin. However, scalp hair and underlying skin are the most likely areas of contamination following airborne exposure to chemicals. The aim of this study was to investigate the interactions of contaminants with scalp hair and underlying skin using a hybrid in vitro diffusion cell model. The in vitro hybrid test system comprised "curtains" of human hair mounted onto sections of excised porcine skin within a modified diffusion cell. The results demonstrated that hair substantially reduced underlying scalp skin contamination and that hair may provide a limited decontamination effect by removing contaminants from the skin surface. This hybrid test system may have application in the development of improved chemical incident response processes through the evaluation of various hair and skin decontamination strategies.

Indexed as

Carbon RadioisotopesDecontaminationDiffusionHairImage Processing, Computer-AssistedSkinTime FactorsCarbon-14Carbon Radioisotopes

Identifiers

PMID30443008
PMCPMC6237820
OpenAlexW2900085775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.