Evidence map›Paper›PMID 30442760›Full record

ArticleGenetics2019

The Role of Maternal HP1a in Early

Ah Rume Park, Na Liu, Nils Neuenkirchen, Qiaozhi Guo, Haifan Lin

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ah Rume ParkYale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520.
Na LiuYale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520.
Nils NeuenkirchenYale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520.
Qiaozhi GuoYale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520.
Haifan LinYale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520 haifan.lin@yale.edu.
Yale University · USYale Cancer Center · US

Funding

Toward a Central Question in Epigenetics: A Major Epigenetic Programming MechanisDP1CA174418 · NCI · YALE UNIVERSITY · PI LIN, HAIFAN · 2012 to 2014
$2.4M
NCI NIH HHS DP1 CA174418
6 · The paper itself

Abstract

Heterochromatin protein 1a (HP1a) is a highly conserved and versatile epigenetic factor that can both silence and activate transcription. However, the function of HP1a in development has been underinvestigated. Here, we report the role of maternal HP1a in producing maternal transcripts that drive early

Indexed as

Gene Expression Regulation, DevelopmentalMaternal InheritanceAnimalsChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneDrosophilaEmbryonic DevelopmentEpigenesis, GeneticFemaleMaleOogenesisRNA, MessengerChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneRNA, Messengerembryonic mitosisHP1amaternal transcriptomeoogenesis

Identifiers

PMID30442760
PMCPMC6325692
OpenAlexW2901231434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.