Evidence map›Paper›PMID 30442100›Full record

ArticleBMC medical imaging2018

Gadoxetic acid-enhanced magnetic resonance imaging significantly influences the clinical course in patients with colorectal liver metastases.

B G Sibinga Mulder, K Visser, S Feshtali, A L Vahrmeijer, R J Swijnenburg, H H Hartgrink, R van den Boom, M C Burgmans, J S D Mieog

Abstract read
In one paragraph

Article in BMC medical imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Intraoperative (Contrast-Enhanced) Ultrasound Has the Highest Diagnostic Accuracy of Any Imaging Modality in Resection of Colorectal Liver Metastases.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

B G Sibinga MulderDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
K VisserDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
S FeshtaliDepartment of Radiology, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
A L VahrmeijerDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
R J SwijnenburgDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
H H HartgrinkDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
R van den BoomDepartment of Radiology, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
M C BurgmansDepartment of Radiology, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands.
J S D MieogDepartment of Surgery, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands. j.s.d.mieog@lumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGadoxetic acid (Primovist™)-enhanced magnetic resonance imaging (P-MRI) scans have higher accuracy and increased detection of small colorectal liver metastases (CRLM) compared to CT scans or conventional MRI scans. But, P-MRI scans are still inconsistently acquired in the diagnostic work up of patients with CRLM. The aim of this study was to determine the influence of P-MRI scans on treatment plan proposition and subsequently the clinical course of the patient.

methodsEighty-three consecutive patients with potentially resectable CRLM based on a conventional CT scan underwent P-MRI scanning prior to treatment. Treatment plans proposed by the multidisciplinary team were compared before and after P-MRI scanning and related to the final treatment and diagnosis, the accuracy for the CT scan and P-MRI scan was calculated.

resultsP-MRI scans led to a change of treatment in 15 patients (18%) and alteration of extensiveness of local therapy in another 17 patients (20%). All changes were justified leading to an accuracy of 93% for treatment proposition based on P-MRI scan, compared to an accuracy of 75% for the CT scan.

conclusionsP-MRI scans provide additional information that can aid in proposing the most suitable treatment for patients with CRLM and might prevent short-term reintervention.

Indexed as

AgedAntineoplastic ProtocolsClinical Decision-MakingClinical ProtocolsColorectal NeoplasmsContrast MediaFemaleGadolinium DTPAHumansLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityTomography, X-Ray ComputedContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPAColorectal liver metastasesPrimovist MRITreatment proposition

Identifiers

PMID30442100
PMCPMC6238306

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.