Evidence map›Paper›PMID 30441844›Full record

ArticleInternational journal of molecular sciences2018

Gadolinium Chloride Rescues Niemann⁻Pick Type C Liver Damage.

Andrés D Klein, Juan Esteban Oyarzún, Cristian Cortez, Silvana Zanlungo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Understanding and Treating Niemann-Pick Type C Disease: Models Matter.International journal of molecular sciences · 2020
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Andrés D KleinCentro de Genética y Genómica, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7590943, Chile. andresklein@udd.cl.ORCID 0000-0002-9951-2174
Juan Esteban OyarzúnDepartamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile. jeoyarzu@uc.cl.
Cristian CortezCenter for Genomic and Bioinformatic, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile. Cristian.cortezplaza@umayor.cl.ORCID 0000-0003-1887-0808
Silvana ZanlungoDepartamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile. szanlungo@uc.cl.ORCID 0000-0001-8383-9829
Pontificia Universidad Católica de Chile · CLUniversidad del Desarrollo · CLUniversidad Mayor · CL

Funding

Exploring Neurological Effects and Life Experiences of Language Deprivation in the Deaf Community of the Dominican RepublicR21TW011508 · FIC · UNIVERSITY OF ROCHESTER · PI DYE, TIMOTHY DE VER, HALL, WYATTE CHRISTOPHER · 2019 to 2020
$373k
European Union's Horizon 2020 research and innovation programme (RISE) under the Marie Skłodowska-Curie grant agreement 734825Fondo Nacional de Desarrollo Científico y Tecnológico 1150816Fondo Nacional de Desarrollo Científico y Tecnológico 1180337
6 · The paper itself

Abstract

Niemann⁻Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the

Indexed as

AnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 MoleculeEndocytosisGadoliniumIntracellular Signaling Peptides and ProteinsKupffer CellsMiceMice, Inbred BALB CNiemann-Pick C1 ProteinNiemann-Pick Disease, Type CProteinsAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 antigen, humanCD68 MoleculeGadoliniumgadolinium chlorideIntracellular Signaling Peptides and ProteinsNiemann-Pick C1 ProteinNpc1 protein, mouseProteinscholesterolgadolinium chlorideliver diseaseNiemann–Pick type C diseasetherapeutic option

Identifiers

PMID30441844
PMCPMC6274821
OpenAlexW2900508190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.