Evidence map›Paper›PMID 30441839›Full record

ArticleMicromachines2018

On-Chip Tunable Cell Rotation Using Acoustically Oscillating Asymmetrical Microstructures.

Lin Feng, Bin Song, Deyuan Zhang, Yonggang Jiang, Fumihito Arai

Abstract read
In one paragraph

Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Magnetic-Assisted Control of Eggs and Embryos via Zona Pellucida-Linked Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lin FengSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. linfeng@buaa.edu.cn.ORCID 0000-0002-5158-3862
Bin SongSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. songb@buaa.edu.cn.ORCID 0000-0002-2610-0697
Deyuan ZhangSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. zhangdy@buaa.edu.cn.
Yonggang JiangSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. jiangyg@buaa.edu.cn.ORCID 0000-0003-1979-996X
Fumihito AraiBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China. arai@mech.nagoya-u.ac.jp.ORCID 0000-0002-2508-1615

Funding

Beihang University ZG216S1751Beihang University ZG226S188DThe Natural Science Foundation of Beijing 17L20128
6 · The paper itself

Abstract

The precise rotational manipulation of cells and other micrometer-sized biological samples is critical to many applications in biology, medicine, and agriculture. We describe an acoustic-based, on-chip manipulation method that can achieve tunable cell rotation. In an acoustic field formed by the vibration of a piezoelectric transducer, acoustic streaming was generated using a specially designed, oscillating asymmetrical sidewall shape. We also studied the nature of acoustic streaming generation by numerical simulations, and our simulation results matched well with the experimental results. Trapping and rotation of diatom cells and swine oocytes were coupled using oscillating asymmetrical microstructures with different vibration modes. Finally, we investigated the relationship between the driving voltage and the speed of cell rotation, showing that the rotational rate achieved could be as large as approximately 1800 rpm. Using our device, the rotation rate can be effectively tuned on demand for single-cell studies. Our acoustofluidic cell rotation approach is simple, compact, non-contact, and biocompatible, permitting rotation irrespective of the optical, magnetic, or electrical properties of the specimen under investigation.

Indexed as

acoustic streamingacoustic wavescell rotationmicromachineon-chip manipulation

Identifiers

PMID30441839
PMCPMC6265899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.