Evidence map›Paper›PMID 30441806›Full record

ArticleMolecules (Basel, Switzerland)2018

Tumidulin, a Lichen Secondary Metabolite, Decreases the Stemness Potential of Colorectal Cancer Cells.

Yi Yang, Suresh R Bhosle, Young Hyun Yu, So-Yeon Park, Rui Zhou, İsa Taş, Chathurika D B Gamage, Kyung Keun Kim, Iris Pereira, Jae-Seoun Hur and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. The Significance of Aldehyde Dehydrogenase 1 in Cancers.International journal of molecular sciences · 2024
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  11. Review
  12. Establishment ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  13. Antitumoral Properties of Natural Products.Molecules (Basel, Switzerland) · 2020
    Article
  14. Article
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  16. α-Pyrone and Sterol Constituents ofJournal of natural products · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Yi YangCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. yangyi_520@hotmail.com.
Suresh R BhosleCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. bhoslesuresh1005@gmail.com.
Young Hyun YuCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. chmyyh@gmail.com.
So-Yeon ParkCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. sinbu17@naver.com.ORCID 0000-0001-6663-8160
Rui ZhouCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. zhourui274@hotmail.com.
İsa TaşCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. mr.isatas@gmail.com.ORCID 0000-0001-5306-8584
Chathurika D B GamageCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. chathurika.gamage@gmail.com.
Kyung Keun KimMedical Research Center for Gene Regulation, Brain Korea 21 Project, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju 61469, Korea. kimkk@chonnam.ac.kr.
Iris PereiraInstitute of Biological Sciences, Universidad de Talca, Talca 747-721, Chile. ipereira@utalca.cl.
Jae-Seoun HurKorean Lichen Res. Institute, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. jshur1@sunchon.ac.kr.
Hyung-Ho HaCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. hhha@sunchon.ac.kr.
Hangun KimCollege of Pharmacy, Sunchon National University, 255 Jungang-ro, Sunchon, Jeonnam 57922, Korea. hangunkim@sunchon.ac.kr.
Sunchon National University · KRChonnam National University · KRUniversity of Talca · CL

Funding

Korea Forest Service 2017024A00-1720-BA01National Research Foundation of Korea NRF-2015R1A4A1041219National Research Foundation of Korea NRF-2016R1C1B2007494National Research Foundation of Korea NRF-2018M3A9A8023762National Research Foundation of Korea NRF-2018R1D1A1B07042608
6 · The paper itself

Abstract

Lichens produce various unique chemicals that are used in the pharmaceutical industry. To screen for novel lichen secondary metabolites that inhibit the stemness potential of colorectal cancer cells, we tested acetone extracts of 11 lichen samples collected in Chile. Tumidulin, isolated from

Indexed as

Antineoplastic Agents, PhytogenicBiomarkersCell Line, TumorColorectal NeoplasmsGene Expression Regulation, NeoplasticHumansLichensMolecular StructureNeoplastic Stem CellsPlant ExtractsSignal TransductionTumor Cells, CulturedAntineoplastic Agents, PhytogenicBiomarkersPlant Extractscolorectal cancer cellslichenoncogenesecondary metabolitesstemness potentialtranscriptional regulationtumidulin

Identifiers

PMID30441806
PMCPMC6278574
OpenAlexW2901963868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.