Evidence map›Paper›PMID 30441757›Full record

ReviewViruses2018

Recent Advances in Zika Virus Vaccines.

Himanshu Garg, Tugba Mehmetoglu-Gurbuz, Anjali Joshi

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  7. Review
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  10. Review
  11. Drugs for the Treatment of Zika Virus Infection.Journal of medicinal chemistry · 2020
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Pre-Clinical Pregnancy Models for Evaluating Zika Vaccines.Tropical medicine and infectious disease · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Himanshu GargCenter of Emphasis in Infectious Diseases, Department of Biomedical Science, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA. himanshu.garg@ttuhsc.edu.
Tugba Mehmetoglu-GurbuzCenter of Emphasis in Infectious Diseases, Department of Biomedical Science, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA. tugba.gurbuz@ttuhsc.edu.
Anjali JoshiCenter of Emphasis in Infectious Diseases, Department of Biomedical Science, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA. anjali.joshi@ttuhsc.edu.
Texas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent outbreaks of Zika virus (ZIKV) infections and associated microcephaly in newborns has resulted in an unprecedented effort by researchers to target this virus. Significant advances have been made in developing vaccine candidates, treatment strategies and diagnostic assays in a relatively short period of time. Being a preventable disease, the first line of defense against ZIKV would be to vaccinate the highly susceptible target population, especially pregnant women. Along those lines, several vaccine candidates including purified inactivated virus (PIV), live attenuated virus (LAV), virus like particles (VLP), DNA, modified RNA, viral vectors and subunit vaccines have been in the pipeline with several advancing to clinical trials. As the primary objective of Zika vaccination is the prevention of vertical transmission of the virus to the unborn fetus, the safety and efficacy requirements for this vaccine remain unique when compared to other diseases. This review will discuss these recent advances in the field of Zika vaccine development.

Indexed as

AnimalsClinical Trials as TopicDisease Transmission, InfectiousDrug DiscoveryDrug Evaluation, PreclinicalHumansViral VaccinesZika VirusZika Virus InfectionViral Vaccinesclinical trialsflavivirusesvaccinesvirus like particlesZika virusZIKV

Identifiers

PMID30441757
PMCPMC6267279
OpenAlexW2900691750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.