Evidence map›Paper›PMID 30440649›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2018

Graph-Based Models of Cortical Axons for the Prediction of Neuronal Response to Extracellular Electrical Stimulation.

Clayton S Bingham, Jean-Marie C Bouteiller, Dong Song, Theodore W Berger

Abstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clayton S Bingham
Jean-Marie C Bouteiller
Dong Song
Theodore W Berger

Funding

Predictive modeling of bioelectric activity on mammalian multilayered neuronal stU01GM104604 · NIGMS · UNIVERSITY OF UTAH · PI BERGER, THEODORE W., LAZZI, GIANLUCA · 2012 to 2016
$2.8M
PREDICTIVE MODELING OF BIOELECTRIC ACTIVITY ON MAMMALIAN MULTILAYERED NEURONAL STRUCTURES IN THE PRESENCE OF SUPRAPHYSIOLOGICAL ELECTRIC FIELDSU01EB025830 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERGER, THEODORE W., LAZZI, GIANLUCA · 2018 to 2021
$2.7M
NIBIB NIH HHS U01 EB025830NIGMS NIH HHS U01 GM104604
6 · The paper itself

Abstract

Over the past decade, many important insights to brain function have been obtained through clever application of detailed compartmental model neurons. New computing capabilities brought opportunities to study large networks of model neurons. Certain applications for these models, such as extracellular electrical stimulation, demand a very high degree of biological realism. While dendrites and somatic morphology may be obtained from explicit reconstructions, this approach is less useful for axonal structures, which are more difficult to characterize across a neuronal population. The purpose of this paper is to extend neuronal morphology generative models to highly branched axon terminal arbors as well as to present a clear use-case for such models in the study of cortical tissue response to externally applied electric fields. The results of this work are (i) presentation and quantitative/qualitative description of generated fibers and (ii) an extracellular electrical stimulation strength-duration study.

Indexed as

AxonsModels, NeurologicalAction PotentialsElectric Stimulation

Identifiers

PMID30440649
PMCPMC6464815

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.