Evidence map›Paper›PMID 30440000›Full record

Trial reportPloS one2018

HIV cascade of care in Greece: Useful insights from additional stages.

Georgia Vourli, Georgios Nikolopoulos, Vasilios Paparizos, Athanasios Skoutelis, Symeon Metallidis, Panagiotis Gargalianos, Antonios Papadopoulos, Maria Chini, Nikolaos V Sipsas, Mina Psychogiou and 8 more

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Access of People Living with HIV to Testing Services in Greece: A Challenge for Equity in Care.International journal of environmental research and public health · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Georgia VourliDept of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-9727-2808
Georgios NikolopoulosMedical School, University of Cyprus, Nicosia, Cyprus.
Vasilios PaparizosAIDS Unit, Clinic of Venereologic & Dermatologic Diseases, Athens University, Medical School, Syngros Hospital, Athens, Greece.
Athanasios SkoutelisInfectious Diseases & HIV Division, Dept of Internal Medicine, Evangelismos Athens General Hospital, Athens, Greece.
Symeon MetallidisAristotle University HIV Unit, AHEPA University Hospital, Thessaloniki, Greece.
Panagiotis GargalianosInfectious Diseases Unit, 1st Dept of Medicine, "G. Gennimatas" Athens General Hospital, Athens, Greece.
Antonios Papadopoulos4th Dept of Internal Medicine, Athens Medical School, Attikon University Hospital, Athens, Greece.ORCID 0000-0003-4735-2620
Maria ChiniInfectious Diseases Unit, Red Cross General Hospital of Athens, Athens, Greece.
Nikolaos V SipsasPathophysiology Department, "Laikon" General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-6955-3453
Mina Psychogiou"Laikon" Athens General Hospital and Athens University, Medical School, Athens, Greece.
Georgios ChrysosInfectious Disease Unit, "Tzaneio" General Hospital of Piraeus, Piraeus, Greece.
Helen SambatakouInfectious Disease Unit, 2nd Dpt. of Internal Medicine, Athens University, Medical School, Hippokration General Hospital, Athens, Greece.ORCID 0000-0001-8904-076X
Charalambos GogosInfectious Diseases Section, 1st Dept of Internal Medicine, Patras University Hospital, Patras, Greece.
Olga KatsarouBlood Transfusion Unit, and National Reference Centre for Congenital Bleeding Disorders, Laikon General Hospital, Athens, Greece.
Dimitra ParaskevaHIV office, Hellenic Center of Disease Control and Prevention, Athens, Greece.
Nikos DedesPositive voice, Non-Governmental Organization, Athens, Greece.
Giota TouloumiDept of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Greek HIV Prevention Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAiming to eliminate HIV infection, UNAIDS has set a global "90-90-90" target by 2020. We sought to construct a 6-stages HIV Cascade of Care (CoC) in Greece, overall and by risk group, to assess risk-group and stage-specific progress in achieving the UNAIDS target. PATIENTS AND

methodsCombining data from the HIV/AIDS surveillance system and a population-based HIV cohort study, the CoC included: i) number of people living with HIV (PLHIV) by end of 2013; ii) proportion of PLHIV ever diagnosed; iii) proportion of diagnosed linked-to-care iv) proportion of linked-to-care ever initiating antiretroviral therapy (ART); v) proportion of treated who retained-in-care vi) proportion of those retained-in-care who were virally suppressed (≤200 copies/mL) at their last visit (01/07/2012-31/12/2013).

resultsIn 2013, 14147 PLHIV were in Greece. Overall, proportions of each stage in the cascade were: 78.4% diagnosed; 86% linked-to-care; 78.5% initiated ART; 86.4% retained-in-care, and 87.1% virally suppressed. Totally, 42.6% of all PLHIV were virally suppressed. The percentage diagnosed was lower among heterosexual men and women (heterosexuals) than in MSM (men who have sex with men) or PWID (people who inject drugs). Most MSM were linked to care (97.2% of diagnosed) while a substantial proportion of PWID were not (80.8% of diagnosed). Once treated, PWID remained in care in similar proportions to MSM. Unlike PWID, a high proportion of the retained in care MSM and heterosexuals achieved viral suppression.

conclusionsAt the end of 2013, we identified gaps in the HIV CoC in Greece, which differed across risk groups. Targeted interventions are critical in optimizing early diagnosis and timely linkage. A 6-stage CoC, stratified by risk group, can inform strategic public health planning in improving HIV treatment outcomes.

Indexed as

Delivery of Health CareHeterosexualityHIV-1Homosexuality, MaleAnti-Retroviral AgentsFemaleGreeceHIV InfectionsHumansMaleRisk FactorsAnti-Retroviral Agents

Identifiers

PMID30440000
PMCPMC6237384

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.