ArticlePloS one2018
Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic review and meta-analysis of clinical studies.European journal of pharmacology · 2021Pooled it
- COVID-19 and healthcare workers: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Pooled it
- Treatment of severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (COVID-19): a systematic review ofTheranostics · 2021Pooled it
- Prevalence of Headache in Patients With Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of 14,275 Patients.Frontiers in neurology · 2020Pooled it
- Opportunity for severe and critical COVID-19 pneumonia treatment with corticosteroids: a retrospective cohort study.Journal of thoracic disease · 2024Article
- Smart secretion management to protect nurses from COVID19 and other infectious diseases.Nursing in critical care · 2022Article
- Article
- Patient follow-up after discharge after COVID-19 pneumonia: Considerations for infectious control.Journal of medical virology · 2020Review
- Extracorporeal Membrane Oxygenation (ECMO) in Critically Ill Patients with Coronavirus Disease 2019 (COVID-19) Pneumonia and Acute Respiratory Distress Syndrome (ARDS).Medical science monitor : international medical journal of experimental and clinical research · 2020Review
- Letter: Neurological Implications of COVID-19 and Lessons Learned From Prior Epidemics and Pandemics.Neurosurgery · 2020Article
- Physical and mental health impacts of COVID-19 on healthcare workers: a scoping review.International journal of emergency medicine · 2020Article
- ECMO use in COVID-19: lessons from past respiratory virus outbreaks-a narrative review.Critical care (London, England) · 2020Review
- COVID-19: a novel coronavirus and a novel challenge for critical care.Intensive care medicine · 2020Article
- Critically ill patients with COVID-19 in Hong Kong: a multicentre retrospective observational cohort studyCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2020Article
- Use of Venovenous Extracorporeal Membrane Oxygenation in Critically-Ill Patients With COVID-19.Frontiers in medicine · 2020Article
- Advances in respiratory virus therapeutics - A meeting report from the 6th isirv Antiviral Group conference.Antiviral research · 2019Review
- Nosocomial outbreak of the Middle East Respiratory Syndrome coronavirus: A phylogenetic, epidemiological, clinical and infection control analysis.Travel medicine and infectious diseaseArticle
Corrections and comments
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Authors and funding
25 authors at 15 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMiddle East Respiratory Syndrome Coronavirus (MERS-CoV) leads to healthcare-associated transmission to patients and healthcare workers with potentially fatal outcomes.
aimWe aimed to describe the clinical course and functional outcomes of critically ill healthcare workers (HCWs) with MERS.
methodsData on HCWs was extracted from a multi-center retrospective cohort study on 330 critically ill patients with MERS admitted between (9/2012-9/2015). Baseline demographics, interventions and outcomes were recorded and compared between survivors and non-survivors. Survivors were approached with questionnaires to elucidate their functional outcomes using Karnofsky Performance Status Scale.
findingsThirty-Two HCWs met the inclusion criteria. Comorbidities were recorded in 34% (11/32) HCW. Death resulted in 8/32 (25%) HCWs including all 5 HCWs with chronic renal impairment at baseline. Non-surviving HCW had lower PaO2/FiO2 ratios 63.5 (57, 116.2) vs 148 (84, 194.3), p = 0.043, and received more ECMO therapy compared to survivors, 9/32 (28%) vs 4/24 (16.7%) respectively (p = 0.02).Thirteen of the surviving (13/24) HCWs responded to the questionnaire. Two HCWs confirmed functional limitations. Median number of days from hospital discharge until the questionnaires were filled was 580 (95% CI 568, 723.5) days.
conclusionApproximately 10% of critically ill patients with MERS were HCWs. Hospital mortality rate was substantial (25%). Patients with chronic renal impairment represented a particularly high-risk group that should receive extra caution during suspected or confirmed MERS cases clinical care assignment and during outbreaks. Long-term repercussions of critical illness due to MERS on HCWs in particular, and patients in general, remain unknown and should be investigated in larger studies.
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