Evidence map›Paper›PMID 30433886›Full record

ReviewAmerican journal of physical medicine & rehabilitation2019

Myths and Facts of In-Office Regenerative Procedures for Tendinopathy.

Alyssa Neph, Kentaro Onishi, James H-C Wang

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in American journal of physical medicine & rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04299802 (A Prospective Randomized Comparison Study on the Effects of Percutaneous Ultrasonic Tenotomy Versus Leukocyte-Rich Platelet Rich Plasma for Refractory Gluteal Tendinopathy), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04299802 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

A Prospective Randomized Comparison Study on the Effects of Percutaneous Ultrasonic Tenotomy Versus Leukocyte-Rich Platelet Rich Plasma for Refractory Gluteal Tendinopathy

TypeinterventionalSponsorAndrews Research & Education FoundationRan2020 to 2020Enrolled0ConditionsGluteal Tendinitis, Trochanteric Bursitis, TendinopathyArmsLeukocyte-Rich Platelet-Rich Plasma, Percutaneous Ultrasonic Tenotomy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alyssa NephFrom the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (AN, KO); and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (KO, JH-CW).
Kentaro Onishi
James H-C Wang
Jacobson Holman (United States) · US

Funding

Repair of tendinopathic tendonsR01AR061395 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, JAMES H-C. · 2011 to 2015
$1.8M
The role of TSCs in the degenerative tendinopathy induced by mechanical loadingR01AR065949 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, JAMES H-C. · 2015 to 2019
$1.7M
HMGB1 Mediates the Onset of Loading-Induced Tendon InjuryR21AR070340 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, JAMES H-C. · 2016 to 2017
$374k
NIAMS NIH HHS R01 AR061395NIAMS NIH HHS R01 AR065949NIAMS NIH HHS R21 AR070340
6 · The paper itself

Abstract

Tendinopathy carries a large burden of musculoskeletal disorders seen in both athletes and aging population. Treatment is often challenging, and progression to chronic tendinopathy is common. Physical therapy, nonsteroidal anti-inflammatory drugs, and corticosteroid injections have been the mainstay of treatment but are not optimal given that most tendon disorders seem to involve degenerative changes in addition to inflammation. The field of regenerative medicine has taken the forefront, and various treatments have been developed and explored including prolotherapy, platelet rich plasma, stem cells, and percutaneous ultrasonic tenotomy. However, high-quality research with standardized protocols and consistent controls for proper evaluation of treatment efficacy is currently needed. This will make it possible to provide recommendations on appropriate treatment options for tendinopathy.

Indexed as

Ambulatory CarePhysical Therapy ModalitiesHumansTendinopathy

Identifiers

PMID30433886
PMCPMC6517092
OpenAlexW2901793246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.