ReviewThe British journal of radiology2019
Diffusion-weighted imaging in rectal cancer: current applications and future perspectives.
Review in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 2 of them syntheses that pooled it.
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Who cites it
89 citing papers in PubMed, 2 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Machine learning in predicting pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer using MRI: a systematic review and meta-analysis.The British journal of radiology · 2024Pooled it
- Guideline
- Quantitative MRI T1 relaxation time as a biomarker of complete response in rectal cancer six weeks after neoadjuvant therapy: a prospective study.Clinical and translational radiation oncology · 2026Article
- Predicting locoregional treatment failure in anal cancer using multivariable clinical-imaging models.Clinical and translational radiation oncology · 2026Article
- Prognostic prediction model for rectal cancer based on CMS subtype indicators and SHAP-based interpretable analysis.Abdominal radiology (New York) · 2026Article
- MRI to guide clinical management of rectal cancer: updated consensus recommendations from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR)-PART I primary staging.European radiology · 2026Article
- Bisacodyl micro-enema before MRI of rectal tumors: effects on rectum, image quality and patient acceptance.European radiology · 2026Article
- Advancing MRI diagnostic practices in rectal cancer: exploring the impact of web-based multi-reader study participation.Abdominal radiology (New York) · 2026Article
- Diffusion-weighted imaging in rectal cancer MRI from theory to practice.Abdominal radiology (New York) · 2026Review
- Deep learning reconstruction accelerated reduced field-of-view DWI in rectal cancer: mucosa-submucosa-muscularis visualization and T staging.European radiology experimental · 2026Article
- Prognostic significance of systemic inflammatory indices in squamous cell carcinoma of the anal canal: A retrospective cohort study.Rare tumors · 2026Article
- Magnetic resonance imaging differentiating benign from malignant bone and soft tissue tumors and assessing Ki-67 expression using APT and DWI tools.Frontiers in oncology · 2026Article
- Case Report: Benign colonic schwannoma with restricted diffusion mimicking malignancy.Frontiers in oncology · 2026Article
- Review
- Non-invasive identification of KRAS mutation in rectal cancer using hybrid intravoxel incoherent motion and diffusion kurtosis model.World journal of surgical oncology · 2025Article
- Low b-values in apparent diffusion coefficient calculations overestimate diffusion in rectal cancer.Acta oncologica (Stockholm, Sweden) · 2025Observational
- Apparent diffusion coefficient increases during short course radiotherapy in rectal tumours: Results from a multicentre longitudinal trial.Physics and imaging in radiation oncology · 2025Article
- Intravoxel incoherent motion-derived histogram analysis for quantitative evaluation of tumor budding and prognostic stratification in rectal cancer.European radiology · 2025Article
- Early response prediction during radiotherapy in rectal cancer using sequential diffusion-weighted imaging at a magnetic resonance image-guided linear accelerator.Physics and imaging in radiation oncology · 2025Article
- Pretreatment intravoxel incoherent motion histogram metrics and clinical characteristics for prediction of perineural invasion status and survival in patients with rectal cancer.Insights into imaging · 2025Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes current applications and clinical utility of diffusion-weighted imaging (DWI) for rectal cancer and in addition provides a brief overview of more recent developments (including intravoxel incoherent motion imaging, diffusion kurtosis imaging, and novel postprocessing tools) that are still in more early stages of research. More than 140 papers have been published in the last decade, during which period the use of DWI have slowly moved from mainly qualitative (visual) image interpretation to increasingly advanced methods of quantitative analysis. So far, the largest body of evidence exists for assessment of tumour response to neoadjuvant treatment. In this setting, particularly the benefit of DWI for visual assessment of residual tumour in post-radiation fibrosis has been established and is now increasingly adopted in clinics. Quantitative DWI analysis (mainly the apparent diffusion coefficient) has potential, both for response prediction as well as for tumour prognostication, but protocols require standardization and results need to be prospectively confirmed on larger scale. The role of DWI for further clinical tumour and nodal staging is less well-defined, although there could be a benefit for DWI to help detect lymph nodes. Novel methods of DWI analysis and post-processing are still being developed and optimized; the clinical potential of these tools remains to be established in the upcoming years.
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