ArticleMagnetic resonance in medicine2019
3D gradient echo snapshot CEST MRI with low power saturation for human studies at 3T.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 81 citations in OpenAlex.
- Amide proton transfer-weighted CEST MRI for radiotherapy target delineation of glioblastoma: a prospective pilot study.European radiology experimental · 2024Trial
- Effective Modeling of Continuous WaveMagnetic resonance in medicine · 2026Article
- Diagnostic Accuracy of APTw and NOEw MRI Metrics for IDH Mutation and 1p/19q Codeletion Prediction in Gliomas.NMR in biomedicine · 2026Article
- Dynamic glucose-enhanced MRI in brain tumors.Magma (New York, N.Y.) · 2026Review
- CEST-MRI assessment of locally advanced pMMR rectal cancer for prediction of immune activation status following radiotherapy.European radiology · 2026Article
- Differentiation between glioblastomas and solid brain metastases using amide proton transfer-weighted (APTw) MRI with and without fluid suppression.Magma (New York, N.Y.) · 2026Article
- Microstructural MRI combined with metabolic MRI to evaluate the progression-free survival of patients with glioblastoma at the early follow-up after tumor treating fields: a pilot study.BMC medical imaging · 2026Article
- Investigation of Endogenous Renal CEST Contrast and the Influence of Respiratory Motion on a Clinical 3 Tesla MRI: An In Vivo and In Vitro Study.Magnetic resonance in medicine · 2026Article
- Chemical exchange saturation transfer MRI for neurodegenerative diseases: An update on clinical and preclinical studies.Neural regeneration research · 2026Article
- Evaluating the effectiveness of distortion self-correction for CEST-EPI.Magnetic resonance in medicine · 2026Article
- Field strength-dependent sensitivity of chemical exchange saturation transfer: a methodological comparison of 3 Tesla and 7 Tesla in a clinical cohort.Brain communications · 2026Article
- CEST Contrasts Exhibit Significant Regional Variations in the Human Brain at 3 T.NMR in biomedicine · 2025Article
- Relaxation-compensated chemical exchange saturation transfer MRI in the cervical spinal cord at 3T: An application in multiple sclerosis.Neuroimage. Reports · 2025Article
- Toward Noninvasive High-Resolution In Vivo pH Mapping in Brain Tumors byNMR in biomedicine · 2025Article
- Mitigation of TRadiology advances · 2025Article
- Multiparametric Chemical Exchange Saturation Transfer MRI Detects Metabolic Changes in Mild Cognitive Impairment Cases at 3.0 Tesla.Neurochemical research · 2024Article
- Fast and motion-robust saturation transfer MRI with inherent BMagnetic resonance in medicine · 2024Article
- Reproducibility of 3D chemical exchange saturation transfer (CEST) contrasts in the healthy brain at 3T.Scientific reports · 2024Article
- Whole-cerebrum guanidino and amide CEST mapping at 3 T by a 3D stack-of-spirals gradient echo acquisition.Magnetic resonance in medicine · 2024Article
- Multipool-CEST and CEST-based pH assessment as predictive tools for glioma grading, IDH mutation, 1p/19q codeletion, and MGMT promoter methylation in gliomas.Frontiers in oncology · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeFor clinical implementation, a chemical exchange saturation transfer (CEST) imaging sequence must be fast, with high signal-to-noise ratio (SNR), 3D coverage, and produce robust contrast. However, spectrally selective CEST contrast requires dense sampling of the Z-spectrum, which increases scan duration. This article proposes a compromise: using a 3D snapshot gradient echo (GRE) readout with optimized CEST presaturation, sampling, and postprocessing, highly resolved Z-spectroscopy at 3T is made possible with 3D coverage at almost no extra time cost.
methodsA 3D snapshot CEST sequence was optimized for low-power CEST MRI at 3T. Pulsed saturation was optimized for saturation power and saturation duration. Spectral sampling and postprocessing (B
resultsLow-power saturation was achieved by a train of 80 pulses of duration t
conclusionA sophisticated CEST tool ready for clinical application was developed and tested for feasibility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.