Evidence map›Paper›PMID 30430766›Full record

ArticlePhysiological reports2018

Effects of hypoestrogenism and/or hyperaldosteronism on myocardial remodeling in female mice.

Patricia Rouet-Benzineb, Régine Merval, Evelyne Polidano

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. A Review of Calcineurin Biophysics with Implications for Cardiac Physiology.International journal of molecular sciences · 2021
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Patricia Rouet-BenzinebINSERM U942, Paris Diderot University, Paris, France.
Régine MervalINSERM U942, Paris Diderot University, Paris, France.
Evelyne PolidanoINSERM U942, Paris Diderot University, Paris, France.
Inserm · FRDélégation Paris 7 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the potential adverse effects of hyperaldosteronism and/or hypoestrogenism on cardiac phenotype, and examined their combined effects in female mice overexpressing cardiac aldosterone synthase (AS). We focused on some signaling cascades challenging defensive responses to adapt and/or to survive in the face of double deleterious stresses, such as Ca

Indexed as

AldosteroneAnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CollagenCytochrome P-450 CYP11B2Endoplasmic Reticulum StressEstrogensFemaleHeartHeart RateHyperaldosteronismMAP Kinase Signaling SystemMiceMyocardiumOvariectomyAldosteroneCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CollagenCytochrome P-450 CYP11B2EstrogensReceptors, EstrogenAldosteronecalcium homeostasiscardiac remodelingER stresshypoestrogenismredox signaling

Identifiers

PMID30430766
PMCPMC6236131
OpenAlexW2901645946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.