Evidence map›Paper›PMID 30430019›Full record

ArticleGastroenterology report2018

The role of visceral adipose tissue on improvement in insulin sensitivity following Roux-en-Y gastric bypass: a study in Chinese diabetic patients with mild and central obesity.

Lei Zhao, Liyong Zhu, Zhihong Su, Weizheng Li, Pengzhou Li, Yong Liu, Shengping Liu, Shaihong Zhu

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lei ZhaoDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Liyong ZhuDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Zhihong SuDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Weizheng LiDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Pengzhou LiDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Yong LiuDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Shengping LiuDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Shaihong ZhuDepartment of General Surgery, Third Xiangya Hospital, Central South University, No 138 Tongzipo Road, Changsha, Hunan, China.
Central South University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost Chinese patients with type 2 diabetes mellitus (T2DM) have mild obesity and central obesity. Central obesity is combined with insulin resistance. The aim of this study was to assess the effect of abdominal adipose tissue on insulin-sensitivity improvement after Roux-en-Y gastric bypass (RYGB) in Chinese diabetic patients with mild and central obesity.

methodsSeventeen T2DM patients with a mean body mass index of 30.3 kg/m

resultsIndices of peripheral insulin sensitivity, including glucose-disposal rate (M value) and glucose infusion rate, were significantly increased after RYGB. Body-fat mass, VAT and SAT were significantly reduced after RYGB. The pre-operative M value was significantly correlated with VAT mass (

conclusionsA significant correlation was observed between increased peripheral insulin sensitivity and decreased VAT following RYGB in Chinese patients with mild and central obesity. VAT and SAT were significantly decreased with improved insulin sensitivity after RYGB. VAT mass may be considered as an indication for gastric bypass during patient selection.

Indexed as

gastric bypasshyperinsulinemic-euglycemic clampInsulin sensitivitynon-morbid obesitytype 2 diabetes mellitusvisceral adipose tissue

Identifiers

PMID30430019
PMCPMC6225828
OpenAlexW2889605214

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.