Evidence map›Paper›PMID 30429883›Full record

ArticleTheranostics2018

Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles.

Christian J Konopka, Marcin Wozniak, Jamila Hedhli, Agata Ploska, Aaron Schwartz-Duval, Anna Siekierzycka, Dipanjan Pan, Gnanasekar Munirathinam, Iwona T Dobrucki, Leszek Kalinowski and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
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  6. Review
  7. In vivo optical molecular imaging of inflammation and immunity.Journal of molecular medicine (Berlin, Germany) · 2021
    Review
  8. Review
  9. Article
  10. Quantitative imaging of the receptor for advanced glycation end-products in prostate cancer.European journal of nuclear medicine and molecular imaging · 2020
    Article
  11. Article
  12. Imaging techniques in nanomedical research.European journal of histochemistry : EJH · 2020
    Article
  13. Progress of RAGE Molecular Imaging in Alzheimer's Disease.Frontiers in aging neuroscience · 2020
    Review
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Christian J KonopkaDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Marcin WozniakDepartment of Medical Laboratory Diagnostics and Central Bank of Frozen Tissues & Genetic Specimens, Medical University of Gdansk, Gdansk, Poland.
Jamila HedhliDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Agata PloskaBeckman Institute for Advanced Science and Technology, Urbana, IL.
Aaron Schwartz-DuvalDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Anna SiekierzyckaDepartment of Medical Laboratory Diagnostics and Central Bank of Frozen Tissues & Genetic Specimens, Medical University of Gdansk, Gdansk, Poland.
Dipanjan PanDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Gnanasekar MunirathinamDepartment of Biomedical Sciences, University of Illinois College of Medicine, Rockford, IL.
Iwona T DobruckiBeckman Institute for Advanced Science and Technology, Urbana, IL.
Leszek KalinowskiDepartment of Medical Laboratory Diagnostics and Central Bank of Frozen Tissues & Genetic Specimens, Medical University of Gdansk, Gdansk, Poland.
Lawrence W DobruckiDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Gdańsk Medical University · PLUniversity of Illinois Urbana-Champaign · USIllinois College · US

Funding

Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
NIBIB NIH HHS T32 EB019944
6 · The paper itself

Abstract

The receptor for advanced glycation end-products (RAGE) is central to multiple disease states, including diabetes-related conditions such as peripheral arterial disease (PAD). Despite RAGE's importance in these pathologies, there remains a need for a molecular imaging agent that can accurately assess RAGE levels

Indexed as

AnimalsAntigens, NeoplasmCopper RadioisotopesGlycation End Products, AdvancedHumansHuman Umbilical Vein Endothelial CellsLysineMiceMitogen-Activated Protein KinasesMolecular ImagingMultimodal ImagingNanoparticlesSerum Albumin, HumanAntigens, NeoplasmCopper RadioisotopesGlycation End Products, AdvancedLysineMitogen-Activated Protein KinasesMOK protein, humanN(6)-carboxymethyllysineSerum Albumin, Humanhindlimb ischemiainflammationmultimodal imagingPET-CTreceptor for advanced glycation end-products

Identifiers

PMID30429883
PMCPMC6217059
OpenAlexW2898321653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.