Evidence map›Paper›PMID 30429850›Full record

ArticleFrontiers in immunology2018

Rainbow Trout Erythrocytes

Sara Puente-Marin, Ivan Nombela, Veronica Chico, Sergio Ciordia, Maria Carmen Mena, Julio Coll, Luis Mercado, Maria Del Mar Ortega-Villaizan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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  7. Transcriptome Analysis ofInternational journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sara Puente-MarinInstituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, Spain.
Ivan NombelaInstituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, Spain.
Veronica ChicoInstituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, Spain.
Sergio CiordiaUnidad de Proteómica, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Maria Carmen MenaUnidad de Proteómica, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Julio CollInstituto Nacional de Investigaciones Agrarias, Biotecnología, Madrid, Spain.
Luis MercadoInstituto de Biología, Pontificia Universidad Católica de Valparaíso Valparaíso, Chile.
Maria Del Mar Ortega-VillaizanInstituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, Spain.
Universitat de Miguel Hernández d'Elx · ESCentro Nacional de Biotecnología · ESInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESPontificia Universidad Católica de Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fish red blood cells (RBCs), are integral in several biologic processes relevant to immunity, such as pathogen recognition, pathogen binding and clearance, and production of effector molecules and cytokines. So far, one of the best strategies to control and prevent viral diseases in aquaculture is DNA immunization. DNA vaccines (based on the rhabdoviral glycoprotein G [gpG] gene) have been shown to be effective against fish rhabdoviruses. However, more knowledge about the immune response triggered by DNA immunization is necessary to develop novel and more effective strategies. In this study, we investigated the role of fish RBCs in immune responses induced by DNA vaccines. We show for the first time that rainbow trout RBCs express gpG of viral hemorrhagic septicaemia virus (VHSV) (GVHSV) when transfected with the DNA vaccine

Indexed as

AnimalsAntibodies, ViralCell LineErythrocytesFish DiseasesFish ProteinsGene Expression RegulationGlycoproteinsHemorrhagic Septicemia, ViralImmunityImmunizationInterferon Type INovirhabdovirusOncorhynchus mykissTransfectionVaccines, DNAAntibodies, ViralFish ProteinsGlycoproteinsInterferon Type IVaccines, DNAViral ProteinsViral VaccinesDNA vaccineerythrocytesimmune responseproteomerainbow troutred blood cellstranscriptomeVHSV glycoprotein G

Identifiers

PMID30429850
PMCPMC6220650
OpenAlexW2898684441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.