ArticleFrontiers in neurology2018
Homotopic Connectivity in Early Pontine Infarction Predicts Late Motor Recovery.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Altered Static and Dynamic Functional Network Connectivity and Combined Machine Learning in Stroke.Brain topography · 2025Article
- Mechanisms of how sarcopenia affects functional outcomes in acute ischaemic stroke.Brain communications · 2025Article
- A comparative study of interhemispheric functional connectivity in patients with basal ganglia ischemic stroke.Frontiers in aging neuroscience · 2024Article
- Alterations of dynamic and static brain functional activities and integration in stroke patients.Frontiers in neuroscience · 2023Article
- The functional and structural neural correlates of dynamic balance impairment and recovery in persons with acquired brain injury.Scientific reports · 2022Article
- Increased cortical-medulla functional connectivity is correlated with swallowing in dysphagia patients with subacute infratentorial stroke.NeuroImage. Clinical · 2022Article
- Brain Functional Topology Alteration in Right Lateral Occipital Cortex Is Associated With Upper Extremity Motor Recovery.Frontiers in neurology · 2022Article
- Altered Coupling Between Cerebral Blood Flow and Voxel-Mirrored Homotopic Connectivity Affects Stroke-Induced Speech Comprehension Deficits.Frontiers in aging neuroscience · 2022Article
- Voxel-Mirrored Homotopic Connectivity Associated With Change of Cognitive Function in Chronic Pontine Stroke.Frontiers in aging neuroscience · 2021Article
- Disrupted Regional Cerebral Blood Flow and Functional Connectivity in Pontine Infarction: A Longitudinal MRI Study.Frontiers in aging neuroscience · 2020Article
- An imbalance between functional segregation and integration in patients with pontine stroke: A dynamic functional network connectivity study.NeuroImage. Clinical · 2020Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Connectivity-based methods are essential to explore brain reorganization after a stroke and to provide meaningful predictors for late motor recovery. We aim to investigate the homotopic connectivity alterations during a 180-day follow-up of patients with pontine infarction to find an early biomarker for late motor recovery prediction. In our study, resting-state functional MRI was performed in 15 patients (11 males, 4 females, age: 57.87 ± 6.50) with unilateral pontine infarction and impaired motor function during a period of 6 months (7, 14, 30, 90, and 180 days after stroke onset). Clinical neurological assessments were performed using the Fugl-Meyer scale (FM).15 matched healthy volunteers were also recruited. Whole-brain functional homotopy in each individual scan was measured by voxel-mirrored homotopic connectivity (VMHC) values. Group-level analysis was performed between stroke patients and normal controls. A Pearson correlation was performed to evaluate correlations between early VMHC and the subsequent 4 visits for behavioral measures during day 14 to day 180. We found in early stroke (within 7 days after onset), decreased VMHC was detected in the bilateral precentral and postcentral gyrus and precuneus/posterior cingulate cortex (PCC), while increased VMHC was found in the hippocampus/amygdala and frontal pole (
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