ArticleFrontiers in physiology2018
Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation-Implications for Abdominal Aortic Aneurysm Susceptibility.
Open access · goldAbstract read
In one paragraph
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 49 citations in OpenAlex.
- Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction.Radiology. Cardiothoracic imaging · 2024Trial
- Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026Review
- E-cigarette Aerosol Containing Nicotine Increases Aortic Stiffness in Young Mice.Cardiovascular toxicology · 2026Article
- Review
- Nicotine promotes AngII-induced abdominal aortic aortopathies in female and male mice: role of sex hormones.Clinical science (London, England : 1979) · 2025Article
- Sexual Dimorphism in Abdominal Aortic Aneurysm-Insights from Clinical and Experimental Studies.Journal of vascular diseases · 2025Article
- The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus.Cardiovascular diabetology · 2025Article
- Nicotine Impairs Smooth Muscle cAMP Signaling and Vascular Reactivity.Microcirculation (New York, N.Y. : 1994) · 2024Article
- Angiotensin Receptor-Neprilysin Inhibition (Sacubitril/Valsartan) Reduces Structural Arterial Stiffness in Middle-Aged Mice.Journal of the American Heart Association · 2024Article
- Nicotine Potentially Alters Endothelial Inflammation and Cell Adhesion viaJournal of cardiovascular development and disease · 2023Article
- Ethanol Enhances Endothelial Rigidity by Targeting VE-Cadherin-Implications for Acute Aortic Dissection.Journal of clinical medicine · 2023Article
- Article
- E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1.Cardiovascular research · 2023Article
- Effects of inhaled β‑caryophyllene on vascular stiffness in smokers: A randomized, double‑blind, placebo‑controlled trial.Experimental and therapeutic medicine · 2023Article
- Nicotine Affects Murine Aortic Stiffness and Fatigue Response During Supraphysiological Cycling.Journal of biomechanical engineering · 2022Article
- The Biological Effects of Smoking on the Formation and Rupture of Intracranial Aneurysms: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2022Review
- Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.Archives of toxicology · 2021Article
- No Effect of Hypercholesterolemia on Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression.Biomolecules · 2021Article
- Dynamic Crosstalk between Vascular Smooth Muscle Cells and the Aged Extracellular Matrix.International journal of molecular sciences · 2021Review
- MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening.Molecular therapy. Nucleic acids · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 11 institutions in 3 countries.
Markus U WagenhäuserCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Isabel N SchellingerMolecular and Translational Vascular Medicine, Department of Cardiology and Pneumology, Heart Center at the University Medical Center Göttingen, Göttingen, Germany.
Takuya YoshinoCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Kensuke ToyamaCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Yosuke KayamaCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Alicia DengCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Sabina P GuentherDepartment of Cardiac Surgery, University Hospital Munich, Ludwig-Maximilian-University, Munich, Germany.
Anne PetzoldMolecular and Translational Vascular Medicine, Department of Cardiology and Pneumology, Heart Center at the University Medical Center Göttingen, Göttingen, Germany.
Joscha MulorzCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Pireyatharsheny MulorzCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Gerd HasenfußGerman Center for Cardiovascular Research e.V., Göttingen, Germany.
Wiebke IbingDepartment of Vascular and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Margitta ElversDepartment of Vascular and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Andreas SchusterMolecular and Translational Vascular Medicine, Department of Cardiology and Pneumology, Heart Center at the University Medical Center Göttingen, Göttingen, Germany.
Anand K RamasubramanianDepartment of Biomedical, Chemical and Materials Engineering, San Jose State University, San Jose, CA, United States.
Matti AdamCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Hubert SchelzigDepartment of Vascular and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Joshua M SpinCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Uwe RaazMolecular and Translational Vascular Medicine, Department of Cardiology and Pneumology, Heart Center at the University Medical Center Göttingen, Göttingen, Germany.
Philip S TsaoCardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.
Cardiovascular Institute of the South · USStanford University · USGerman Centre for Cardiovascular Research · DEHeinrich Heine University Düsseldorf · DEVA Palo Alto Health Care System · USDüsseldorf University Hospital · DELeipzig University · DELudwig-Maximilians-Universität München · DERoyal North Shore Hospital · AUSan Jose State University · USUniversitätsmedizin Göttingen · DE
Funding
MicroRNA Regulation of Nicotine Accelerated AAAsR01HL122939 · NHLBI · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI TSAO, PHILIP S · 2014 to 2017
$1.4MEffects of Inhaled Nicotine on Vascular miR-24 Activity and AAA FormationR56HL135654 · NHLBI · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI TSAO, PHILIP S · 2017 to 2017
$300kBLRD VA I01 BX002641NHLBI NIH HHS R01 HL122939NHLBI NIH HHS R56 HL135654
Abstract
PubMed holds no abstract for this paper.
Indexed as
AAAe-cigarettesmouse modelnicotinesegmentationstiffness
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.