Evidence map›Paper›PMID 30429735›Full record

ArticleSaudi journal of anaesthesia

Comparative evaluation of analgesic sparing efficacy between dexmedetomidine and clonidine used as adjuvant to ropivacaine in thoracic paravertebral block for patients undergoing breast cancer surgery: A prospective, randomized, double-blind study.

Anindya Mukherjee, Anjan Das, Nairita Mayur, Chiranjib Bhattacharyya, Hirak Biswas, Tapobrata Mitra, Sandip Roybasunia, Subrata Kumar Mandal

RetractedOpen access · diamondAbstract readRetracted Publication
In one paragraph

Article in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Retraction.Saudi journal of anaesthesia
    Article
4 · The record

Corrections and comments

  • Retraction · 2020-05-30Falsification/Fabrication of Data · Investigation by Journal/Publisher · Objections by Third Party · Plagiarism of/in Article ·
  • Retracted
5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anindya MukherjeeDepartment of Anaesthesiology, NRS Medical College, Kolkata, West Bengal, India.
Anjan DasDepartment of Anaesthesiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
Nairita MayurDepartment of Anaesthesiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
Chiranjib BhattacharyyaDepartment of Anaesthesiology, IPGMER, Kolkata, West Bengal, India.
Hirak BiswasDepartment of Anaesthesiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
Tapobrata MitraDepartment of Anaesthesiology, Murshidabad Medical College, Berhampore, West Bengal, India.
Sandip RoybasuniaDepartment of Anaesthesiology, Murshidabad Medical College, Berhampore, West Bengal, India.
Subrata Kumar MandalDepartment of Anaesthesiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
College of Medicine & Sagore Dutta Hospital · INMurshidabad Medical College and Hospital · INInstitute of Post Graduate Medical Education and Research · INMedical College and Hospital, Kolkata · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThoracic paravertebral block (TPVB) is an effective method for intra- and post-operative pain management in thoracic surgeries. For a long time, various adjuvants have been tried for prolonging the duration of TPVB.

objectiveIn this prospective study, we have compared the analgesic sparing efficacy of dexmedetomidine and clonidine, two α MATERIALS AND

methodsForty-four breast cancer surgery patients undergoing general anesthesia (GA) were randomly divided into Group C and Group D (

resultsIntraoperative fentanyl and propofol requirement was significantly less in dexmedetomidine group than clonidine. The requirement of diclofenac sodium was also significantly less and later in Group D than Group C. Hemodynamics, and side effects were comparable among two groups.

conclusionDexmedetomidine provided better intraoperative as well as postoperative analgesia than clonidine when administered with ropivacaine in TPVB before breast cancer surgery patients without producing remarkable side effects.

Indexed as

Clonidinedexmedetomidinegeneral anesthesiathoracic paravertebral blockvisual analog scale

Identifiers

PMID30429735
PMCPMC6180706
OpenAlexW2904920976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.