Evidence map›Paper›PMID 30429667›Full record

SynthesisBiochemia medica2018

Red blood cell distribution width in pregnancy: a systematic review.

Panagiotis Paliogiannis, Angelo Zinellu, Arduino A Mangoni, Giampiero Capobianco, Salvatore Dessole, Pier Luigi Cherchi, Ciriaco Carru

Abstract readSystematic Review
In one paragraph

Synthesis in Biochemia medica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  5. Observational
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  7. Circulating vascular endothelial growth factor receptor-3, a pro-lymphangiogenic and pro-angiogenic mediator, is decreased in pre-eclampsia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  8. Article
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  11. Review
  12. Review
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  17. Observational
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Panagiotis PaliogiannisDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Angelo ZinelluDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Arduino A MangoniDepartment of Clinical Pharmacology, College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Giampiero CapobiancoDepartment of Clinical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Salvatore DessoleDepartment of Clinical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Pier Luigi CherchiDepartment of Clinical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Ciriaco CarruDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anisocytosis has been associated with the severity and prognosis of several acute and chronic diseases, as well as physiological conditions such as pregnancy. Anisocytosis is quantified by the red blood cell distribution width (RDW), expressed as the ratio, multiplied by 100, between the standard deviation (SD) of red blood cell volumes and the mean corpuscular volume, or as the SD of erythrocyte volumes (RDW-SD). The aim of the present review was to report the state of the art on the physiological values and the putative diagnostic and prognostic roles of RDW in complicated pregnancy. Literature research for articles published in the last ten years was conducted in Pubmed, Web of Science, ClinicalTrials.gov, and Scopus databases. Abstracts were independently screened by two investigators. If relevant, full articles were retrieved. References, in these articles, citing relevant reviews or original studies were also accessed to identify additional eligible studies. Any disagreement between the reviewers was resolved by a third investigator. A total of 28 studies were included in the review. These studies reported changes in RDW values during physiological pregnancy, and associations between the RDW and several pregnancy complications including anaemia, preeclampsia, gestational diabetes, and recurrent miscarriage. This review provides background information for establishing physiological and pathological RDW values in pregnancy for diagnostic and prognostic use in clinical practice.

Indexed as

Erythrocyte VolumeErythrocytesFemaleHumansPregnancyanisocytosisgestational diabetespreeclampsiapregnancyRDW

Identifiers

PMID30429667
PMCPMC6214699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.