ArticleProceedings of the National Academy of Sciences of the United States of America2018
Microstructural properties of the vertical occipital fasciculus explain the variability in human stereoacuity.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- What do we know about the Vertical Occipital Fasciculus? A systematic review.Brain structure & function · 2026Pooled it
- Large-scale functional overlap between dorsal and ventral object-responsive networks.Research square · 2026Article
- Neural micro and macrostructural correlates of visual outcomes in children with unilateral cerebral palsy: A fixel-based study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Visual system structural and functional connections during face viewing in body dysmorphic disorder.bioRxiv : the preprint server for biology · 2024Article
- Measurement of paracentral stereopsis using a new method with the binocular open perimeter imovifaJapanese journal of ophthalmology · 2024Article
- Tractometry of Human Visual White Matter Pathways in Health and Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- Distinct rich and diverse clubs regulate coarse and fine binocular disparity processing: Evidence from stereoscopic task-based fMRI.iScience · 2024Article
- Myeloarchitectonic plasticity in elite golf players' brains.Human brain mapping · 2022Article
- Microstructural deficits of the thalamus in major depressive disorder.Brain communications · 2022Article
- Effect of Impaired Stereoscopic Vision on Large-Scale Resting-State Functional Network Connectivity in Comitant Exotropia Patients.Frontiers in neuroscience · 2022Article
- Abnormal effective connectivity in visual cortices underlies stereopsis defects in amblyopia.NeuroImage. Clinical · 2022Article
- The structure of the superior and inferior parietal lobes predicts inter-individual suitability for virtual reality.Scientific reports · 2021Article
- Myeloarchitectonic Asymmetries of Language Regions in the Human Brain.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Occipital Intralobar fasciculi: a description, through tractography, of three forgotten tracts.Communications biology · 2021Article
- Anatomy of nerve fiber bundles at micrometer-resolution in the vervet monkey visual system.eLife · 2020Article
- Perspectives given by structural connectivity bridge the gap between structure and function.Brain structure & function · 2020Article
- Anatomy and white matter connections of the lateral occipital cortex.Surgical and radiologic anatomy : SRA · 2020Article
- Altered functional connectivity of cortical networks in semantic variant Primary Progressive Aphasia.NeuroImage. Clinical · 2020Article
- The visual word form area (VWFA) is part of both language and attention circuitry.Nature communications · 2019Article
- Comparative neuroanatomy: Integrating classic and modern methods to understand association fibers connecting dorsal and ventral visual cortex.Neuroscience research · 2019Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stereopsis is a fundamental visual function that has been studied extensively. However, it is not clear why depth discrimination (stereoacuity) varies more significantly among people than other modalities. Previous studies have reported the involvement of both dorsal and ventral visual areas in stereopsis, implying that not only neural computations in cortical areas but also the anatomical properties of white matter tracts connecting those areas can impact stereopsis. Here, we studied how human stereoacuity relates to white matter properties by combining psychophysics, diffusion MRI (dMRI), and quantitative MRI (qMRI). We performed a psychophysical experiment to measure stereoacuity and, in the same participants, we analyzed the microstructural properties of visual white matter tracts on the basis of two independent measurements, dMRI (fractional anisotropy, FA) and qMRI (macromolecular tissue volume; MTV). Microstructural properties along the right vertical occipital fasciculus (VOF), a major tract connecting dorsal and ventral visual areas, were highly correlated with measures of stereoacuity. This result was consistent for both FA and MTV, suggesting that the behavioral-structural relationship reflects differences in neural tissue density, rather than differences in the morphological configuration of fibers. fMRI confirmed that binocular disparity stimuli activated the dorsal and ventral visual regions near VOF endpoints. No other occipital tracts explained the variance in stereoacuity. In addition, the VOF properties were not associated with differences in performance on a different psychophysical task (contrast detection). These series of experiments suggest that stereoscopic depth discrimination performance is, at least in part, constrained by dorso-ventral communication through the VOF.
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